Recursive self-feedback to help speech after a stroke in aphasia
Official title: Recursive Self-feedback Procedures for Improving Spontaneous Speech Production in Patients With Chronic Aphasia
Run by University of South Florida · NCT06323629 · Data updated 2026-11-12
Researchers are testing whether stroke survivors with aphasia can improve their everyday speech by listening to and correcting their own spoken responses using tablet-based, self-guided feedback.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 45 (estimated) |
| Sponsor | University of South Florida Academic / other |
| Locations | 1 site (Tampa, Florida) |
| Status | Recruiting |
| Started | August 29, 2024 |
| Main results expected | December 2027 |
| Study ends | December 2027 |
| Registry record updated | September 14, 2026 |
| Trial ID | NCT06323629 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with aphasia due to a left-hemisphere stroke, at least six months post-stroke, and who are native English speakers.
✕Probably not a fit
Individuals with non-aphasia speech disorders, severe cognitive or language comprehension impairments, or other exclusion criteria may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The study tests two versions of a recursive self-feedback treatment for aphasia after left-hemisphere stroke. Participants perform language and cognitive tasks, then receive tablet-based feedback that plays back their own speech and prompts them to correct errors in the next attempt. One version adapts the task difficulty based on performance, while the other remains non-adaptive. Enrollment targets adults with aphasia who are at least six months post-stroke and who are native English speakers. Exclusions include other neurological speech causes, significant sensory or comprehension impairments, and severe cognitive deficits.
Why it matters
Potential benefit: If successful, this approach could help patients improve spontaneous speech using self-guided practice at home with technology.
How similar studies have gone: Previous work in aphasia rehabilitation has explored self-monitoring and feedback strategies, with mixed but promising results for language outcomes.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 6 months post left hemisphere stroke * Aphasia due to left hemisphere stroke * Dominant English speaker Exclusion Criteria: * Speech-language deficits due to neurological insults such as Parkinson's disease, neurodegenerative conditions etc. * Uncorrected sensory impairments. * Language comprehension impairment. * Severe cognitive impairment.
Where it's running
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Brain and Aphasia Recovery Lab, PCD 1030, Department of Communication Sciences and Disorders, University of South Florida
Tampa, Florida, United States Recruiting
Study contacts
- Principal investigator: Gerald C. Imaezue, PhD — University of South Florida
- Study coordinator: Gerald C. Imaezue, PhD
- Email: gimaezue@usf.com
- Phone: (813)974-2464
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Tailoring rTMS for Post-Stroke Aphasia Based on Language Profile
A non-drug brain stimulation approach is tested to see if customizing rTMS targets improves language recovery in people with aphasia after a left-brain stroke.
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tDCS in Rehab for Stroke-Related Aphasia: A Practical Implementation
This study tests whether a 20-minute anodal tDCS session paired with speech therapy can be integrated into routine inpatient and outpatient rehab for people who recently had a stroke and now have aphasia.
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This project will try to decode imagined Mandarin speech, including lexical tones, from high-density brain-surface (ECoG) signals in adult patients who are having clinically indicated cortical electrode placement.
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Digital speech-therapy app Zenicom for subacute post-stroke aphasia in Korean speakers
This trial will try the Zenicom digital speech-therapy app alongside conventional therapy to see if it helps Korean adults with aphasia after a recent (within 3 months) stroke.
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Deep phenotyping to explore recovery in young adults after stroke
This project will test whether a detailed health and sample-collection approach (deep phenotyping) is practical and acceptable for people aged 18–55 who have had a stroke.
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TMS plus language therapy to improve word-finding after left-hemisphere stroke
Researchers will try excitatory transcranial magnetic stimulation combined with semantic feature analysis language therapy to improve word-finding in adults with aphasia after left-hemisphere stroke.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.