REACH-OUT: A technology-based approach to improve blood pressure in reproductive-age women at community clinics
Official title: A Technology-based, Primary Care Strategy to Optimize Blood Pressure Before Pregnancy: The REACH-OUT Trial
Run by Northwestern University · NCT07540143 · Data updated 2026-11-12
This trial tests a technology-enabled strategy to help young women with hypertension manage their BP and adhere to blood pressure medications in Federally Qualified Health Centers.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 44 Years |
| Sex | Women only |
| Enrollment | 350 (estimated) |
| Sponsor | Northwestern University Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | June 16, 2026 |
| Main results expected | April 1, 2029 |
| Study ends | June 30, 2030 |
| Registry record updated | November 9, 2026 |
| Trial ID | NCT07540143 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Biologically female, aged 18–44, English or Spanish speaking, on antihypertensive therapy, with elevated BP, and internet access, at participating sites.
✕Probably not a fit
Individuals who do not have elevated BP or are not currently on antihypertensive therapy may derive little to no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
REACH-OUT is a patient-randomized trial evaluating a multicomponent, technology-based program designed for reproductive-aged women with hypertension receiving care at FQHCs. Clinicians receive EHR-based decision support to review antihypertensive prescriptions and contraceptive use, flag contraindications, and guide counseling on safety and adherence. For the intervention group, participants get educational materials, a home BP monitor with training, access to a patient portal tool for logging BP, and a brief survey to identify adherence barriers; a patient navigator provides tailored support as needed. The study will compare REACH-OUT versus usual care in 350 English- or Spanish-speaking, non-pregnant women on antiHTN therapy with elevated BP to see if systolic BP improves within 3 months and whether medication adherence and contraindicated drug use decrease.
Why it matters
Potential benefit: If successful, this approach could improve blood pressure control and adherence among young women with hypertension using a scalable, technology-assisted model in primary care.
How similar studies have gone: Prior studies suggest technology-enabled, EHR-assisted strategies can improve BP management, though this exact multicomponent approach in young, underserved women is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * biologically female * age 18-44 * English or Spanish-speaking * prescribed an antiHTN * have a systolic BP \>140 or diastolic BP\>90 at their index visit * have access to the internet Exclusion Criteria: * not pregnant or within 3 months postpartum * severe, uncorrectable vision, hearing, or cognitive impairment that would preclude study consent or participation
Where it's running
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Northwestern University
Chicago, Illinois, United States Recruiting
Study contacts
- Principal investigator: Stacy C Bailey, PhD, MPH — Northwestern University
- Study coordinator: Stacy C Bailey, PhD MPH
- Email: stacy-bailey@northwestern.edu
- Phone: (312) 503-3272
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.