Clinical trial Recruiting at 1 site Observational Ages 18 and up

Radiotherapy for limb neoplasms

Official title: Radiotherapy Treatments for Neoplasms of the Limbs

Run by European Institute of Oncology · NCT06335251 · Data updated 2026-11-12

This study looks at how well radiotherapy works for people with tumors in their arms or legs to find the best treatment options.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment3000 (estimated)
SponsorEuropean Institute of Oncology
Academic / other
Locations1 site (Milan)
StatusRecruiting
StartedFebruary 22, 2018
Main results expectedDecember 31, 2025
Study endsDecember 31, 2025
Registry record updatedAugust 28, 2025
Trial IDNCT06335251 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients receiving radiotherapy for primary or secondary neoplasms localized in the upper or lower limbs.

Probably not a fit

Patients receiving radiotherapy for conditions outside of the limbs will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study involves patients treated at the European Institute of Oncology who receive radiotherapy for neoplasms located in the upper or lower limbs. Approximately 60% of patients with neoplasms undergo radiotherapy as part of their treatment, which may be combined with other systemic or surgical therapies. The study aims to collect data on treatment outcomes and tolerability to identify optimal treatment strategies for various types of bone and soft tissue tumors, as well as metastatic conditions. By analyzing this data, the research seeks to enhance understanding of effective radiotherapy protocols.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies for patients with limb neoplasms, enhancing their outcomes and quality of life.

How similar studies have gone: Other studies have shown success in using radiotherapy for limb neoplasms, but this specific observational approach is less common.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients treated with radiotherapy for curative, palliative, neo-adjuvant, and adjuvant purposes in the upper and lower limbs for:

   Primary bone tumors, Primary soft tissue tumors, Primary tumors of the cardio-circulatory system, Primary tumors of the lymphatic system, Primary tumors of the nervous system and skin, Secondary metastases from various origins localized in that district.
2. Signed informed consent

Exclusion Criteria:

1\. Radiotherapy in districts other than limbs.

Where it's running

  • European Institute of Oncology
    Milan, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.