Radiotherapy for limb neoplasms

Radiotherapy Treatments for Neoplasms of the Limbs

Observational European Institute of Oncology · NCT06335251

This study looks at how well radiotherapy works for people with tumors in their arms or legs to find the best treatment options.

Quick facts

Study typeObservational
Enrollment3000 (estimated)
Ages18 Years and up
SexAll
SponsorEuropean Institute of Oncology Academic / other
Locations1 site (Milan)
Trial IDNCT06335251 on ClinicalTrials.gov

What this trial studies

This observational study involves patients treated at the European Institute of Oncology who receive radiotherapy for neoplasms located in the upper or lower limbs. Approximately 60% of patients with neoplasms undergo radiotherapy as part of their treatment, which may be combined with other systemic or surgical therapies. The study aims to collect data on treatment outcomes and tolerability to identify optimal treatment strategies for various types of bone and soft tissue tumors, as well as metastatic conditions. By analyzing this data, the research seeks to enhance understanding of effective radiotherapy protocols.

Who should consider this trial

Good fit: Ideal candidates include patients receiving radiotherapy for primary or secondary neoplasms localized in the upper or lower limbs.

Not a fit: Patients receiving radiotherapy for conditions outside of the limbs will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies for patients with limb neoplasms, enhancing their outcomes and quality of life.

How similar studies have performed: Other studies have shown success in using radiotherapy for limb neoplasms, but this specific observational approach is less common.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients treated with radiotherapy for curative, palliative, neo-adjuvant, and adjuvant purposes in the upper and lower limbs for:

   Primary bone tumors, Primary soft tissue tumors, Primary tumors of the cardio-circulatory system, Primary tumors of the lymphatic system, Primary tumors of the nervous system and skin, Secondary metastases from various origins localized in that district.
2. Signed informed consent

Exclusion Criteria:

1\. Radiotherapy in districts other than limbs.

Where this trial is running

Milan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Bone NeoplasmsBone Metastases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.