Quadroiliac Plane Block for Pain Relief After Kidney Transplant
Official title: Analgesic Efficacy of Ultrasound-Guided Quadroiliac Plane Block Versus Surgical Wound Infiltration in Patients Undergoing Renal Transplantation: A Prospective, Randomized, Double-Blind, Controlled Clinical Trial
Run by Kanuni Sultan Suleyman Training and Research Hospital · NCT07716566 · Data updated 2026-11-12
This trial tests whether an ultrasound-guided unilateral quadroiliac plane block can reduce pain and opioid use after kidney transplant compared with standard surgical wound infiltration.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | Women only |
| Enrollment | 60 (estimated) |
| Sponsor | Kanuni Sultan Suleyman Training and Research Hospital Academic / other |
| Locations | 1 site (Istanbul, Istanbul) |
| Status | Recruiting |
| Started | July 20, 2026 |
| Main results expected | July 20, 2027 |
| Study ends | July 21, 2027 |
| Registry record updated | October 13, 2026 |
| Trial ID | NCT07716566 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–80 undergoing renal transplantation with ASA I–III who can consent.
✕Probably not a fit
Patients with contraindications to regional anesthesia or local anesthetic allergy may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, randomized, double-blind study in adults undergoing renal transplantation. Participants are assigned to receive either a unilateral quadroiliac plane block with 40 mL of 0.25% bupivacaine or surgical wound infiltration with 10 mL of 0.25% bupivacaine. The procedure is performed under anesthesia and outcomes are assessed postoperatively by investigators blinded to group assignment. The aim is to determine if the nerve block provides superior analgesia and reduces opioid requirements. Treatment allocation is concealed and handled by study personnel not involved in outcome assessment.
Why it matters
Potential benefit: If successful, the block could provide better pain control and lower opioid needs after kidney transplant.
How similar studies have gone: Local anesthetic plane blocks in abdominal surgery have shown analgesic benefits in prior studies; this trial extends that approach to renal transplantation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 80 years * American Society of Anesthesiologists physical status I-III * Scheduled to undergo renal transplantation surgery * Ability to understand the study procedures and postoperative assessments * Provision of written informed consent Exclusion Criteria: * Known allergy to bupivacaine or other amide-type local anesthetics * Infection at the planned injection site * Coagulopathy or anticoagulant therapy associated with an unacceptable bleeding risk for regional anesthesia * Sepsis * Severe spinal deformity or anatomical abnormality preventing performance of the quadroiliac plane block * Inability to cooperate or communicate reliably * Cognitive impairment or intellectual disability preventing informed consent or reliable outcome assessment * Altered level of consciousness * Breastfeeding * Refusal to participate
Where it's running
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Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital
Istanbul, Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Engin ihsan Turan, principal investigator
- Email: enginihsan@hotmail.com
- Phone: +905382431114
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.