qCON/qNOX-guided anesthesia for thyroidectomy
Official title: The Effect of qCON/qNOX-Guided Anesthesia Using the Conox Monitor on Clinical Outcomes in Patients Undergoing Thyroidectomy Surgery
Run by Kayseri City Hospital · NCT07445659 · Data updated 2026-11-12
This trial will test whether using the Conox qCON/qNOX monitor during thyroid surgery reduces intraoperative opioid use and speeds recovery for adults having a thyroidectomy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | Kayseri City Hospital Government |
| Locations | 1 site (Kayseri, Kayseri) |
| Status | Recruiting |
| Started | April 10, 2026 |
| Main results expected | June 1, 2026 |
| Study ends | June 30, 2026 |
| Registry record updated | April 20, 2026 |
| Trial ID | NCT07445659 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–70 with ASA physical status I–II scheduled for thyroidectomy who can have EEG electrodes placed and can give informed consent are the ideal candidates.
✕Probably not a fit
Patients with skin lesions that prevent EEG placement, preexisting neurological disorders, an anticipated difficult airway, or those outside the age/ASA criteria are unlikely to receive benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults undergoing thyroidectomy at Kayseri City Hospital will receive either Conox-guided anesthesia with qCON/qNOX monitoring or standard anesthesia management, with maintenance by inhalational agents and opioids and no additional neuromuscular blockers after induction. The primary outcome is intraoperative opioid consumption, with secondary outcomes including recovery time, postoperative agitation rates, and pain scores. Investigators will record qCON and qNOX indices and correlate them with conventional hemodynamic parameters to explore their relationship with nociception and anesthetic depth. Standard eligibility rules apply (age 18–70, ASA I–II) and EEG electrode placement is required unless prevented by skin lesions.
Why it matters
Potential benefit: If successful, Conox-guided anesthesia could reduce opioid use during surgery and shorten recovery and discomfort after thyroidectomy.
How similar studies have gone: Some prior studies of nociception monitoring have shown reduced intraoperative opioid use and better hemodynamic control, but results are mixed and the specific use of qCON/qNOX in thyroidectomy is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients aged 18-70 years * Thyroidectomy cases with ASA physical status I-II * Patients who have provided written informed consent Exclusion Criteria: * Skin lesions preventing EEG electrode placement * Neurological disorders (e.g., epilepsy) * Anticipated difficult airway
Where it's running
-
Kayseri City Hospital
Kayseri, Kayseri, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: çiğdem ünal kantekin, MD — Kayseri City Hospital
- Study coordinator: Çiğdem Ünal Kantekin, MD
- Email: drcgdm@gmail.com
- Phone: +905054433056
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.