Monitoring anesthesia depth and pain response during induction in children
Monitoring the Depth of Anesthesia and Nociception During the Induction of General Anesthesia in Pediatric Patients: a Prospective Observational Study
This project will try a bedside monitor called Conox to measure how deeply children (ages 1–19) are anesthetized and how well their pain is controlled when general anesthesia is started.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 1 Year to 19 Years |
| Sex | All |
| Sponsor | Brno University Hospital Academic / other |
| Locations | 1 site (Brno) |
| Trial ID | NCT07245654 on ClinicalTrials.gov |
What this trial studies
This is an observational study using the Conox device to continuously monitor depth of anesthesia (qCON index) and analgesia during induction of general anesthesia in pediatric patients. Electrodes are placed on the forehead before induction and data are recorded throughout airway management and the operation, with no change to standard anesthetic care. The team will record opioid use, airway management method, occurrences of burst suppression, and postoperative delirium in the recovery room. No experimental interventions are given; the study compares monitored indices with clinical events to characterize monitoring performance.
Who should consider this trial
Good fit: Ideal candidates are pediatric patients aged 1–19 years undergoing elective surgery under general anesthesia with expected duration over 30 minutes and availability of CONOX monitoring.
Not a fit: Patients having very short procedures, those receiving ketamine, emergency cases, or those at sites without CONOX monitoring are unlikely to benefit from the findings.
Why it matters
Potential benefit: If successful, this monitoring approach could help reduce intraoperative awareness episodes and lower the risk of postoperative delirium and inadequate pain control in children.
How similar studies have performed: Processed EEG monitors like BIS and related indices have shown usefulness in adults for guiding anesthetic depth, but pediatric data are more limited and the qCON application in children is less well established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pediatric patients (age 1-19 years) indicated for surgery under general anesthesia with airway management (laryngeal mask, orotracheal intubation, nasotracheal intubation) * CONOX monitoring available Exclusion Criteria: * Age out of range * Use of ketamine during anesthesia care (premedication, analgesic, anesthetic) * Expected duration of surgery less than 30 minutes * CONOX monitoring unavailable
Where this trial is running
Brno
- University Hospital Brno — Brno, Czechia (Recruiting)
Study contacts
- Principal investigator: Petr Štourač, prof.MD.Ph.D — Brno University Hospital
- Study coordinator: Tereza Bonischova, MD
- Email: musilovate@gmail.com
- Phone: 00420724253223
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.