Clinical trial Recruiting at 1 site Interventional Ages 20 to 60

Ultrasound-guided neck blocks to compare pain relief after thyroid surgery

Official title: Comparative Study of Ultrasound Guided Superficial vs Intermediate Cervical Plexus Block for Perioperative Analgesia in Patients Undergoing Thyroid Surgeries.

Run by Menoufia University · NCT07843589 · Data updated 2026-11-12

This study tests whether a superficial ultrasound-guided cervical plexus block provides similar or better pain relief than an intermediate block for people undergoing thyroid surgery.

Quick facts

Study typeInterventional
Ages20 Years to 60 Years
SexAll
Enrollment90 (estimated)
SponsorMenoufia University
Academic / other
Drugs / interventionsradiation
Locations1 site (Alexandria, Shebin Elkom)
StatusRecruiting
StartedOctober 2026
Main results expectedMarch 2027
Study endsMay 2027
Registry record updatedSeptember 29, 2026
Trial IDNCT07843589 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 20–60 years old undergoing elective total thyroidectomy, with ASA I–III, and no contraindications to regional anesthesia.

Probably not a fit

Patients with bleeding disorders, allergy to local anesthetics, diaphragmatic motion issues, high BMI, prior neck surgery or neck injuries, seizures, neck radiation, or those who refuse participation may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares two ultrasound-guided neck nerve blocks given around the time of thyroid surgery to see which offers better pain control. Participants are adults aged 20–60 with ASA I–III status undergoing elective total thyroidectomy. The procedures involve pre-, intra-, and postoperative administration of either a superficial or an intermediate cervical plexus block to assess analgesic efficacy and safety. The study is interventional and conducted at Menoufia University’s Faculty of Medicine, with no listed collaborators. Eligibility requires appropriate health status, no contraindicating neck conditions, and consent to participate.

Why it matters

Potential benefit: If successful, the preferred block could reduce postoperative pain and analgesic need after thyroid surgery.

How similar studies have gone: There is prior research on cervical plexus blocks for neck surgery, but direct comparison between superficial and intermediate blocks for thyroid surgery is less established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with ASA physical status 1 or 2 and 3
* Patients undergoing elective total thyroidectomy (with normal thyroid function tests)
* Patients aged 20 to 60 years of both sexes

Exclusion Criteria:

* Patients with known bleeding diathesis
* History of allergy to local anaesthetics or known diaphragmatic motion abnormalities
* Patient who refuse to participate
* BMI (Body Mass Index) more than 35 kg/m2
* Previous neck surgeries/Burns injury to neck/ contractures in neck
* Patients with known seizure disorder
* Patients with history of radiation exposure on neck.

Where it's running

  • Faculty of medicine Menoufia University
    Alexandria, Shebin Elkom, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.