Program to prevent functional decline in older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The ICOPE program, developed by the World Health Organization, aims to maintain the autonomy of elderly individuals by addressing age-related functional decline. This multicenter, randomized trial compares the effectiveness of the comprehensive ICOPE intervention against usual care for individuals aged 70 and over living at home. Participants will undergo a screening process to identify deficits in six functional domains, followed by personalized care plans if needed. The study includes regular follow-ups to assess functional outcomes over a period of five years.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Participants aged 65 years and older.
2. Participants living independently at home (ADL = 6, except for an occasional urinary abnormality which will be accepted).
3. Participants showing functional decline in at least 2 of the 6 functional domains of ICOPE (mobility, cognition, nutrition, vision, hearing, and psychological well-being) identified using the ICOPE screening tool.
4. Participants affiliated with a social protection system.

Exclusion Criteria:

1. Participants who has already benefited from the ICOPE program or who has completed more than one isolated step 1
2. Participants living in a dependent elderly care facility.
3. Participants with a disability preventing them from reaching the trial examination center without assistance (such as dementia or significant mobility impairment).
4. Participants with hearing, visual, or speech impairments preventing them from understanding instructions or communicating with study staff.
5. Participants with a life-threatening illness with a prognosis of less than 5 years.
6. Participants unable to provide informed written consent.
7. Participants under legal protection, guardianship, or trusteeship.
8. Participants participating in another interventional research study.
9. Participants in a relationship with a person participating in the study.

Where it's running

• Chic
  Castres, France, France Recruiting
• Perpignan Hospital
  Perpignan, France, France Recruiting
• Bigorre Hospital
  Tarbes, France, France Recruiting
• CHU Toulouse
  Toulouse, France, France Recruiting
• Angers University hospital
  Angers, France Recruiting
• Limoges university hospital
  Limoges, France Recruiting

Study contacts

• Principal investigator: Laurent BALARDY, MD — University Hospital, Toulouse
• Study coordinator: Laurent BALARDY, MD
• Email: balardy.l@chu-toulouse.fr
• Phone: 05 61 77 64 95

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Muscle function response to resistance-band training in older adults with low muscle power

  This study tests whether resistance-band exercise plus fitness advice can improve balance and muscle power in older adults with weak leg power.

  Recruiting Brunel University · London · NCT07672834

• L‑serine supplements with or without strength training for older adults

  This trial tries daily L‑serine supplements, alone or combined with supervised strength training, to see if they improve thinking, brain health, and physical fitness in healthy 65–85‑year‑olds.

  Recruiting University of Vienna · Vienna, State of Vienna · NCT07466290

• Personalized 8-week program to support healthier aging with exercise, lifestyle coaching, and targeted supplements

  This program will try a personalized 8-week mix of supervised exercise, sleep and diet coaching, motivational support, and supplements (whey protein, creatine, NMN, fucoidan, multivitamin) for adults aged 50–80 with below-average fitness or cognitive scores.

  Recruiting National University of Singapore · Singapore, Singapore · NCT07451496

• HMB and 2-HOBA to Support Muscle Strength and Thinking in Adults 65+

  This study tests whether taking HMB, 2-HOBA, or both can improve muscle strength and cognitive function in adults over 65.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07419633

• ICOPE INTENSE-K program to improve mobility, thinking, and immune health in older adults

  This program will see if an intensive ICOPE lifestyle program combined with ketone ester supplements (or placebo), plus vitamin D3 and omega‑3, helps older adults with early mobility and thinking problems improve mobility, cognition, and immune-related aging markers.

  Recruiting University Hospital, Toulouse · Toulouse · NCT07048860

• Survey on disability and cognitive impairment in elderly people in Beijing

  This study is trying to find out what factors might lead to disability and memory problems in older adults living in Beijing, so they can help prevent these issues in the future.

  Recruiting Xuanwu Hospital, Beijing · Beijing · NCT06863727

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.