Preventing osteoarthritis after an ACL tear

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of a 6-month virtual education and exercise therapy program called Stop OsteoARthritis (SOAR) for individuals aged 16-35 who have undergone anterior cruciate ligament reconstruction (ACLR) 9-36 months prior. Participants will be randomized to receive either the SOAR program or a minimal intervention control. The study will assess improvements in knee health, including pain, symptoms, function, and quality of life at 6, 12, and 24 months. Additionally, the trial will analyze the cost-effectiveness and implementation of the SOAR program.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Currently live in British Columbia, Canada
* 16-35 years of age (inclusive)
* 9-36-months past a first-time ACLR performed ≤12-months of first-time ACL tear
* Currently not receiving knee care from a health or fitness provider and have no scheduled surgical procedures (any part of the body) that would interfere with exercise during the study.
* Score below a KOOS4 PASS (\<79 points)
* Have daily access to an email address and a computer with internet
* Are willing to wear an activity tracker during the study

Exclusion Criteria:

* Inability to communicate in English
* No medical attention (healthcare provider) time-loss (missed physical activity, sport or work ≥2 occasions) injury to the ACLR knee before the ACL tear
* Previous physician diagnosis of index knee osteoarthritis
* Inflammatory arthritis or other systemic condition
* Lower limb injury, surgery, or intra-articular injection in the past 6-months
* Current pregnancy
* MRI contraindications (i.e., Weight over 400 lbs (MRI machine limit); Pacemaker or any other implanted medical device (i.e., wires, defibrillator, artificial heart valve, an electronic device like a drug infusion pump, electrical stimulator for nerves or bones, coil, catheter, or filter in any blood vessel, ear or eye implant, or stainless steel intrauterine device (IUD); Brain or ferromagnetic aneurysm clip; any other metallic prostheses or shrapnel, bullets, or other metal fragments; injury where a piece of metal lodged in the eye or orbit, or; surgery, medical procedure or tattoos (including tattooed eyeliner) in the last 6 weeks).

Where it's running

• Arthritis Research Canada
  Vancouver, British Columbia, Canada Recruiting
• Sea to Sky Orthopaedics
  Whistler, British Columbia, Canada Recruiting

Study contacts

• Principal investigator: Jackie L Whittaker, BScPT, PhD — University of British Columbia
• Study coordinator: Jackie L Whittaker, BScPT, PhD
• Email: jackie.whittaker@ubc.ca
• Phone: 604-202-1362

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.