PrEP Linkage With Immediate Medications in the Emergency Department

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The program is a pilot to increase PrEP awareness and uptake by initiating rapid-start PrEP in the ED and arranging follow-up with a PrEP clinic. A PrEP navigator approaches eligible ED patients, educates them on PrEP options, and obtains consent for participation. If eligible, participants receive a rapid HIV test (if not recently tested) and start PrEP prescriptions with a plan for ongoing care, including long-acting injectable options where appropriate. The study leverages the hospital’s prior HIV prediction tool and navigation program to identify candidates and facilitate linkage to care.

Why it matters

Who can join: the full rules

Primary study (ED patients):

Inclusion Criteria:

* Able to comprehend and provide signed, written informed consent prior to initiation of study procedures.
* Negative HIV rapid test
* At least one of the following criteria:

  * Requesting PrEP from their ED clinician
  * Score \>75% on the PCCI HIV Prediction Tool
  * Prior bacterial STI diagnosis
  * Seeking STI testing
  * Referred by their ED clinician as someone who otherwise meets a CDC PrEP indication

Exclusion Criteria:

* Known diagnosis of HIV
* Positive HIV rapid test
* Current use of PrEP, which is defined for purposes of this study as use of PrEP in the last 4 weeks
* Known hypersensitivity or allergy to any PrEP modality
* People who do not want to follow with Parkland ID clinic for ongoing PrEP care
* Adults unable to consent, people under the age of 18, women who are known to be pregnant or breast feeding at time of study enrollment, or prisoners

Sub-study subjects (ED clinicians):

Inclusion criteria:

• Clinician in the Parkland ED

Exclusion criteria:

• People under the age of 18 or prisoners.

Where it's running

• Parkland Health
  Dallas, Texas, United States Recruiting

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.