Evaluating laparoscopic right hemihepatectomy for liver cancer
Official title: Textbook Outcomes of Right Hemihepatectomy in Patients With Hepatocellular Carcinoma: a Comparative Study of Laparoscopic and Open Surgery
Run by West China Hospital · NCT06950827 · Data updated 2026-11-12
This study is testing if a less invasive liver surgery for cancer can be safer and lead to better recovery than traditional surgery for people with liver cancer.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | West China Hospital Academic / other |
| Locations | 1 site (Chengdu, Sichuan) |
| Status | Recruiting |
| Started | April 5, 2025 |
| Main results expected | May 10, 2025 |
| Study ends | May 15, 2025 |
| Registry record updated | April 30, 2025 |
| Trial ID | NCT06950827 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older with hepatocellular carcinoma limited to the right half of the liver and adequate preoperative liver function.
✕Probably not a fit
Patients with other types of liver cancer or those requiring extensive surgical interventions beyond laparoscopic hemihepatectomy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on the outcomes of laparoscopic right hemihepatectomy in patients diagnosed with hepatocellular carcinoma. It aims to assess the feasibility and safety of this minimally invasive surgical technique compared to traditional open surgery, which often involves larger incisions and longer recovery times. The study will include patients who meet specific eligibility criteria, including age and liver function status, and will analyze postoperative outcomes to determine the effectiveness of laparoscopic approaches in high-capacity surgical centers.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and faster recovery for patients undergoing liver surgery.
How similar studies have gone: While laparoscopic liver resection has shown promise in various studies, the specific outcomes of laparoscopic right hemihepatectomy remain under investigation, making this study particularly relevant.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥ 18 years old; 2. The lesion is limited to the right half of the liver and diagnosed as hepatocellular carcinoma based on paraffin pathology and immunohistochemistry results; 3. The type of surgery is elective surgery; 4. The patient's preoperative liver function was Child Pugh A or B grade, and the preoperative ASA (American Society of Anesthesiologists) rating was I, II, or III. Exclusion Criteria: 1. Pathological confirmed cholangiocarcinoma, mixed cell carcinoma, or extrahepatic metastatic malignant tumors; 2. Previous history of upper abdominal surgery; 3. Simultaneously undergoing adjacent abdominal organ resection, major vessel and biliary reconstruction surgery, except for the gallbladder; 4. Merge adjacent organ invasions except for the gallbladder, with main blood vessels, bile duct cancer emboli, or distant metastases; 5. Lost to follow-up or loss of primary clinical data.
Where it's running
-
West China Hospital
Chengdu, Sichuan, China Recruiting
Study contacts
- Study coordinator: Jiwei Huang Professor
- Email: huangjiwei@wchscu.cn
- Phone: +86 18980606725
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.