Predicting post-surgery ICU outcomes using IL-6 and blood-count inflammation scores

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational cohort of adult postoperative patients admitted to a single intensive care unit. IL-6 levels will be recorded at ICU admission and at 24 hours, and routine labs will be used to calculate hemogram-derived indices (for example NLR, PLR, SII, SIRI, NMR, CAR, CLR, and mSIS). Clinical severity (APACHE II, SOFA) and comorbidity (Charlson) scores, surgical details, and outcomes including mortality, morbidity, infections, antibiotic use, and duration of mechanical ventilation will be recorded. Analyses will examine associations between biomarkers and outcomes after adjustment for illness severity and other confounders, with no interventions beyond standard care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Postoperative patients admitted to the ICU
* Availability of complete clinical and laboratory data at ICU admission and at 24 hours
* Provision of informed consent by the patient or legally authorized representative

Exclusion Criteria:

* Age \< 18 years
* Thoracic surgery patients
* Cardiac surgery patients

Where it's running

• Recep Erin
  Trabzon, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Ezgi Günaydın, MD
• Email: ezgunaydin@gmail.com
• Phone: +905336834198

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Ventilation During Transport of Mechanically Ventilated Patients After Non-Cardiac Surgery

  This observational study looks at how patients who stay intubated after non-cardiac surgery are ventilated during the move from the operating room to the ICU.

  Recruiting Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva · Alessandria, Italy · NCT07646249

• Predicting Extubation Problems With Machine Learning

  This study tests whether computer models can predict extubation failure in adults on ventilators in the ICU.

  Recruiting Universitas Indonesia · Jakarta, DKI Jakarta and 1 other locations · NCT07918924

• Levetiracetam Dosing in Critically Ill on CRRT

  This study tests how levetiracetam behaves in the bodies of adults on continuous renal replacement therapy to help figure out the best dosing.

  Recruiting Chulalongkorn University · Pathum Wan, Bangkok · NCT07918833

• Respiratory Physiotherapy in Critically Ill Pneumonia Patients

  This study tests whether a structured breathing and chest therapy program can change inflammatory biomarkers in adults with pneumonia in the ICU compared to usual care.

  Recruiting Hospital H+ Queretaro · Querétaro · NCT07909616

• Immersive VR for improving upper limb function in critically ill ICU patients

  This trial tests whether fully immersive virtual reality training added to standard ICU rehabilitation can help improve upper limb strength and coordination in adults with ICU-acquired weakness.

  Recruiting National and Kapodistrian University of Athens · Athens, Attica · NCT07901855

• Prehabilitation with Resistance, Aerobic, or Both Before Colorectal Surgery

  Four pre-surgery exercise options (resistance, aerobic, both, or none) will be tested to see which best reduces complications after colorectal cancer surgery.

  Recruiting Semmelweis University · Budapest · NCT07896174

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.