Postoperative pain relief after breast surgery using regional blocks
Official title: Investigation of the Postoperative Effectiveness of Fascial Plane Blocks Used for Analgesia in Patients Undergoing Breast Surgery: A Prospective Observational Study
Run by Bursa Yuksek Ihtisas Training and Research Hospital · NCT07830446 · Data updated 2026-11-12
This observational study will see how well two regional nerve blocks plus routine care reduce pain and opioid use in adults after elective breast surgery at one center.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | Bursa Yuksek Ihtisas Training and Research Hospital Government |
| Locations | 1 site (Bursa) |
| Status | Recruiting |
| Started | April 1, 2026 |
| Main results expected | February 25, 2027 |
| Study ends | March 1, 2027 |
| Registry record updated | September 23, 2026 |
| Trial ID | NCT07830446 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–80 undergoing elective breast surgery with general anesthesia, and no contraindications to regional anesthesia.
✕Probably not a fit
Patients with allergy to local anesthetics, coagulation disorders, high BMI (>40), infection at the injection site, chronic pain, pregnancy, or communication barriers may not benefit from the blocks or may be unlikely to experience improved analgesia.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective, single-center observational study compares postoperative pain management among three groups: rhomboid intercostal plane block, serratus posterior superior intercostal plane block, and a no-block control. The treating anesthesiologist determines the block strategy as part of routine care, and participants are not randomized. The primary outcome is the total tramadol used via patient-controlled analgesia within 24 hours after surgery, with secondary measures including pain scores at rest and with movement, sensory block levels, postoperative nausea and vomiting, and any block-related complications. Eligibility includes adults 18–80 undergoing elective breast surgery under general anesthesia, and exclusion criteria cover allergy to local anesthetics, coagulation disorders, high BMI, infection at the block site, chronic pain, pregnancy, communication barriers, and emergency surgery. Data will be collected from 90 participants across three cohorts at Bursa Yuksek Ihtisas Training and Research Hospital.
Why it matters
Potential benefit: If successful, the study could identify which regional block approach provides better immediate postoperative pain control and reduces opioid use after breast surgery.
How similar studies have gone: Other observational analyses in regional anesthesia for breast surgery have shown variable but promising reductions in opioid requirements and pain scores.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 to 80 years * American society of anesthesiologists physical status I to III * Undergoing surgery under general anesthesia * Provision of written informed consent * Scheduled for elective breast surgery Exclusion Criteria: * History of allergy to local anesthetic medications * Coagulation disorder * Body mass index greater than 40 kg/m2 * Infection at the block application site * Chronic pain syndrome * Pregnancy * Inability to communicate * Requirement for emergency surgery
Where it's running
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Bursa Yuksek Ihtisas Training and Research Hospital
Bursa, Turkey (Türkiye) Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.