Post Obturation Pain After Root Canal: Bioceramic Sealer vs Resin-Based Sealer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial compares two root canal sealers to see which one leads to less post-obturation pain. Adults aged 18–60 with ASA I–II and symptomatic irreversible pulpitis are eligible and will be randomly assigned to receive either Endoplus (resin-based) or CeraSeal (tricalcium silicate/bioceramic) as the sealer. Procedures are standardized and performed by the principal investigator, including anesthesia, isolation, chemo-mechanical prep, medicament placement, and obturation. The primary outcome is mean post-obturation pain with its standard deviation, measured after treatment. Ethical approval will be obtained, informed consent collected, and participants followed up to ensure safety and data integrity.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* • Patients of age group 18 to 60 years

  * Healthy patients with ASA class 1 and 2
  * Patients of both genders
  * Teeth diagnosed as symptomatic irreversible pulpitis
  * Single as well as multirooted teeth

Exclusion Criteria:

* Teeth with calcified or previously treated canals
* Immunocompromised or mentally handicapped patients
* Pregnant or lactating mothers
* Teeth with periodontal probing depths of 5 mm or more
* Cracked or un restorable teeth
* Teeth where root canal instrumentation could not reach within 2 mm of the radiographic apex

Where it's running

• Armed Force Institute of Dentistry
  Rawalpindi, Punjab Province, Pakistan Recruiting

Study contacts

• Study coordinator: Pooja Kumari
• Email: dhomejapooja@gmail.com
• Phone: 03133422793

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.