Clinical trial Recruiting at 1 site Interventional Ages Any age to 59

Effects of saline temperature on pain after wisdom tooth removal

Official title: Does Saline Irrigation At Different Temperatures Affect Pain, Edema, and Trismus After Impacted Third Molar Surgery: a Clinical Trial

Run by Armed Forces Institute of Dentistry, Pakistan · NCT06741696 · Data updated 2026-11-12

This study tests whether using warm or cold saline during wisdom tooth removal can help reduce pain and improve recovery for patients.

More Post Operative Pain trials

Quick facts

Study typeInterventional
AgesAny age to 59 Years
SexAll
Enrollment48 (estimated)
SponsorArmed Forces Institute of Dentistry, Pakistan
Academic / other
Locations1 site (Rawalpindi, Punjab Province)
StatusRecruiting
StartedOctober 24, 2024
Main results expectedMarch 30, 2025
Study endsMarch 30, 2025
Registry record updatedDecember 19, 2024
Trial IDNCT06741696 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy individuals with bilaterally asymptomatic impacted mandibular third molars who can comply with follow-up requirements.

Probably not a fit

Patients with significant systemic diseases, poor oral hygiene, or those who have recently used analgesics or antibiotics may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the impact of saline irrigation at different temperatures on postoperative pain following the surgical extraction of third molars. A total of 48 healthy patients with bilaterally asymptomatic mandibular third molars were randomly assigned to receive either warm or cold saline during their procedure. Pain levels, swelling, and trismus were assessed at multiple time points post-surgery, and the amount of analgesics consumed was recorded. The study employs various statistical analyses to evaluate the effectiveness of the saline temperature on pain management.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing third molar surgery.

How similar studies have gone: While similar studies on postoperative pain management exist, the specific focus on saline temperature in this context is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:1. Patients who met the requirements of the study, such as attending follow-up sessions and signing the informed consent. 2. Patients with bilateral mandibular asymptomatic vertical third molar teeth with impaction of Class I, level C.22 3. Patients who did not have any significant medical diseases or drug use, were not pregnant, had no allergy, and did not smoke.

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Exclusion Criteria:

1 Patients with complicating systemic disease ( American Society of Anesthesiologists : 3- 6). 2. Patients who have second molars with severe periodontal defect or deep periodontal pocket (probing depth \>4 mm). 3. Patients with poor oral hygiene. 4. Patients with a history of using analgesics 12 hours ago or antibiotics 1 month before. 5. The presence of cysts or tumors around the impacted third molar.

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Where it's running

  • Armed Forces Institute of Dentistry
    Rawalpindi, Punjab Province, Pakistan
    Recruiting

Study contacts

  • Principal investigator: hafsa razzaq razzaq, BDS — Armed Forces Institute of Dentistry , Rawalpindi
  • Study coordinator: hafsa razzaq Razzaq, BDS
  • Email: hafsarazzaq799@gmail.com
  • Phone: 923074614908

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.