Effects of saline temperature on pain after wisdom tooth removal
Official title: Does Saline Irrigation At Different Temperatures Affect Pain, Edema, and Trismus After Impacted Third Molar Surgery: a Clinical Trial
Run by Armed Forces Institute of Dentistry, Pakistan · NCT06741696 · Data updated 2026-11-12
This study tests whether using warm or cold saline during wisdom tooth removal can help reduce pain and improve recovery for patients.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | Any age to 59 Years |
| Sex | All |
| Enrollment | 48 (estimated) |
| Sponsor | Armed Forces Institute of Dentistry, Pakistan Academic / other |
| Locations | 1 site (Rawalpindi, Punjab Province) |
| Status | Recruiting |
| Started | October 24, 2024 |
| Main results expected | March 30, 2025 |
| Study ends | March 30, 2025 |
| Registry record updated | December 19, 2024 |
| Trial ID | NCT06741696 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy individuals with bilaterally asymptomatic impacted mandibular third molars who can comply with follow-up requirements.
✕Probably not a fit
Patients with significant systemic diseases, poor oral hygiene, or those who have recently used analgesics or antibiotics may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the impact of saline irrigation at different temperatures on postoperative pain following the surgical extraction of third molars. A total of 48 healthy patients with bilaterally asymptomatic mandibular third molars were randomly assigned to receive either warm or cold saline during their procedure. Pain levels, swelling, and trismus were assessed at multiple time points post-surgery, and the amount of analgesics consumed was recorded. The study employs various statistical analyses to evaluate the effectiveness of the saline temperature on pain management.
Why it matters
Potential benefit: If successful, this study could lead to improved pain management strategies for patients undergoing third molar surgery.
How similar studies have gone: While similar studies on postoperative pain management exist, the specific focus on saline temperature in this context is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria:1. Patients who met the requirements of the study, such as attending follow-up sessions and signing the informed consent. 2. Patients with bilateral mandibular asymptomatic vertical third molar teeth with impaction of Class I, level C.22 3. Patients who did not have any significant medical diseases or drug use, were not pregnant, had no allergy, and did not smoke. \- Exclusion Criteria: 1 Patients with complicating systemic disease ( American Society of Anesthesiologists : 3- 6). 2. Patients who have second molars with severe periodontal defect or deep periodontal pocket (probing depth \>4 mm). 3. Patients with poor oral hygiene. 4. Patients with a history of using analgesics 12 hours ago or antibiotics 1 month before. 5. The presence of cysts or tumors around the impacted third molar. \-
Where it's running
-
Armed Forces Institute of Dentistry
Rawalpindi, Punjab Province, Pakistan Recruiting
Study contacts
- Principal investigator: hafsa razzaq razzaq, BDS — Armed Forces Institute of Dentistry , Rawalpindi
- Study coordinator: hafsa razzaq Razzaq, BDS
- Email: hafsarazzaq799@gmail.com
- Phone: 923074614908
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Post-operative Pain and Healing After Root Canal Re-Treatment Using Laser-Activated Irrigation vs Sonic or No Activation
This study tests whether laser-activated irrigation or sonic activation helps reduce post-operative pain and improve healing after re-treating a tooth with persistent apical inflammation, compared to conventional needle irrigation.
-
Combined PECS II and PIP blocks vs TPVB for post-mastectomy pain relief
This trial tests whether a combination of PECS II and superficial PIP blocks can provide better or similar pain relief after mastectomy compared with the standard thoracic paravertebral block.
-
Bilateral serratus posterior superior intercostal plane block for pain after on‑pump open‑heart surgery
This trial will test whether a bilateral serratus posterior superior intercostal plane (SPSIP) block can reduce acute postoperative pain and opioid use in adults having on‑pump open‑heart surgery.
-
Supra-inguinal fascia iliaca nerve block for pain after hip replacement
This project will try a supra-inguinal fascia iliaca nerve block during primary total hip replacement to see if it reduces pain and the need for opioids afterward.
-
Comparing oral pregabalin and fentanyl for pain relief after surgery
This study is testing whether taking pregabalin before surgery can help manage pain after laparoscopic gynecologic surgery better than using fentanyl during the procedure.
-
Testing a new gel for pain relief after wisdom tooth extraction
This study is testing a new gel for pain relief after wisdom tooth removal to see if it works better than a placebo and how well it's absorbed in the body.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.