Clinical trial Recruiting at 1 site Observational Ages 25 to 60

Physical profile of cervicogenic headache vs neck pain and healthy people

Official title: A Multidimensional Physical Profile of Cervicogenic Headache: A Cross-Sectional Comparison With Nonspecific Neck Pain and Healthy Controls

Run by Istanbul Medipol University Hospital · NCT07776275 · Data updated 2026-11-12

This observational study tests whether posture, grip strength, muscle stiffness, elasticity, and pressure sensitivity differ among people with cervicogenic headache, chronic neck pain, and healthy controls.

More Chronic Neck Pain trials

Quick facts

Study typeObservational
Ages25 Years to 60 Years
SexAll
Enrollment135 (estimated)
SponsorIstanbul Medipol University Hospital
Academic / other
Locations1 site (Istanbul, Sefaköy)
StatusRecruiting
StartedApril 21, 2026
Main results expectedNovember 8, 2026
Study endsNovember 30, 2026
Registry record updatedNovember 10, 2026
Trial IDNCT07776275 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 25–60 with CGH for at least 3 months, or chronic neck pain for at least 6 months with no headaches, or healthy controls without neck pain or headaches.

Probably not a fit

Individuals with certain comorbid conditions or those not meeting group criteria may not see a benefit from this observational study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will compare adults aged 25–60 across three groups: cervicogenic headache, chronic neck pain without headaches, and healthy controls. They will measure physical characteristics such as posture, grip strength, muscle stiffness, elasticity, and pressure sensitivity to see if CGH has a distinct pattern. Participants will have one visit and will not receive treatment or changes to their usual care. The study will help clarify whether CGH presents a unique physical profile compared with neck pain alone or no neck problems.

Why it matters

Potential benefit: If successful, findings could improve understanding of CGH and help guide future diagnostic or management approaches.

How similar studies have gone: Previous research has explored physical profiles in neck-related conditions, but direct prospective comparisons among CGH, neck pain, and healthy individuals are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
* Inclusion Criteria:
* Aged 25 to 60 years
* Able to provide written informed consent
* Meeting the criteria for one of the following groups:
* Cervicogenic headache: physician diagnosis according to the International Classification of Headache Disorders, 3rd edition, with symptoms lasting at least 3 months
* Chronic nonspecific neck pain: neck pain lasting at least 6 months without headache
* Healthy control: no neck pain or headache

Exclusion Criteria:

* Receipt of physiotherapy for headache or neck pain during the previous 6 months
* Diagnosis of a headache disorder other than cervicogenic headache, including migraine or tension-type headache, or a diagnosis of trigeminal neuralgia
* History of cervical spine surgery or significant cervical trauma
* Current or previous diagnosis of a tumor or cancer
* Serious cardiovascular, cerebrovascular, hematological, metabolic, neurological, or psychiatric disorder
* Rheumatoid arthritis
* Congenital cervical abnormality
* Cervical spondylolisthesis or cervical instability
* Active infection
* Temporomandibular joint dysfunction
* Dizziness or visual disturbance accompanying headache
* Any clinical red flag suggesting serious cervical pathology
* Pregnancy or breastfeeding
* Upper-extremity injury, surgery, or another condition affecting handgrip strength
* Serious musculoskeletal disorder affecting cervical posture or muscle measurements
* Inability to complete the questionnaire-based or instrument-based assessments

Where it's running

  • Medipol Sefaköy Üniversite Hastanesi
    Istanbul, Sefaköy, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.