Physical profile of cervicogenic headache vs neck pain and healthy people
Official title: A Multidimensional Physical Profile of Cervicogenic Headache: A Cross-Sectional Comparison With Nonspecific Neck Pain and Healthy Controls
Run by Istanbul Medipol University Hospital · NCT07776275 · Data updated 2026-11-12
This observational study tests whether posture, grip strength, muscle stiffness, elasticity, and pressure sensitivity differ among people with cervicogenic headache, chronic neck pain, and healthy controls.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 25 Years to 60 Years |
| Sex | All |
| Enrollment | 135 (estimated) |
| Sponsor | Istanbul Medipol University Hospital Academic / other |
| Locations | 1 site (Istanbul, Sefaköy) |
| Status | Recruiting |
| Started | April 21, 2026 |
| Main results expected | November 8, 2026 |
| Study ends | November 30, 2026 |
| Registry record updated | November 10, 2026 |
| Trial ID | NCT07776275 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 25–60 with CGH for at least 3 months, or chronic neck pain for at least 6 months with no headaches, or healthy controls without neck pain or headaches.
✕Probably not a fit
Individuals with certain comorbid conditions or those not meeting group criteria may not see a benefit from this observational study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will compare adults aged 25–60 across three groups: cervicogenic headache, chronic neck pain without headaches, and healthy controls. They will measure physical characteristics such as posture, grip strength, muscle stiffness, elasticity, and pressure sensitivity to see if CGH has a distinct pattern. Participants will have one visit and will not receive treatment or changes to their usual care. The study will help clarify whether CGH presents a unique physical profile compared with neck pain alone or no neck problems.
Why it matters
Potential benefit: If successful, findings could improve understanding of CGH and help guide future diagnostic or management approaches.
How similar studies have gone: Previous research has explored physical profiles in neck-related conditions, but direct prospective comparisons among CGH, neck pain, and healthy individuals are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
* Inclusion Criteria: * Aged 25 to 60 years * Able to provide written informed consent * Meeting the criteria for one of the following groups: * Cervicogenic headache: physician diagnosis according to the International Classification of Headache Disorders, 3rd edition, with symptoms lasting at least 3 months * Chronic nonspecific neck pain: neck pain lasting at least 6 months without headache * Healthy control: no neck pain or headache Exclusion Criteria: * Receipt of physiotherapy for headache or neck pain during the previous 6 months * Diagnosis of a headache disorder other than cervicogenic headache, including migraine or tension-type headache, or a diagnosis of trigeminal neuralgia * History of cervical spine surgery or significant cervical trauma * Current or previous diagnosis of a tumor or cancer * Serious cardiovascular, cerebrovascular, hematological, metabolic, neurological, or psychiatric disorder * Rheumatoid arthritis * Congenital cervical abnormality * Cervical spondylolisthesis or cervical instability * Active infection * Temporomandibular joint dysfunction * Dizziness or visual disturbance accompanying headache * Any clinical red flag suggesting serious cervical pathology * Pregnancy or breastfeeding * Upper-extremity injury, surgery, or another condition affecting handgrip strength * Serious musculoskeletal disorder affecting cervical posture or muscle measurements * Inability to complete the questionnaire-based or instrument-based assessments
Where it's running
-
Medipol Sefaköy Üniversite Hastanesi
Istanbul, Sefaköy, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Fatih Bali, PhD.
- Email: fatihbali@hotmail.com
- Phone: +905323937689
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Effects of Instrument-Assisted Soft Tissue Mobilization vs Post Facilitation Stretch in Chronic Neck Pain
This trial compares two manual therapy techniques, IASTM and Post Facilitation Stretch, to see which better reduces neck pain and improves movement and function in adults with chronic neck pain.
-
Post Isometric Relaxation vs Reciprocal Inhibition for Cervicogenic Headache
This study tests whether two gentle neck muscle techniques, post isometric relaxation and reciprocal inhibition, help people with cervicogenic headache more than a standard physical therapy routine.
-
Kaltenborn vs Maitland Mobilization for Cervicogenic Headache
This trial tests whether Kaltenborn mobilization helps people with cervicogenic headache more than Maitland mobilization.
-
Cervical Epidural Block With or Without Exercises for Chronic Neck Pain
This study tests whether adding cervical stabilization exercises or physical therapy to a cervical epidural block helps reduce neck pain and improve function in adults with chronic neck pain and cervical radiculopathy.
-
Accessory breathing muscles in people with chronic neck pain
This study compares how accessory chest and neck muscles work in people with chronic neck pain vs. healthy individuals to see how they relate to diaphragm function and overall breathing.
-
Breathing new life into neck pain: brain activity and six weeks of physiotherapy
This study tests whether brain activity measured by EEG changes after six weeks of manual therapy and neck exercises in adults with chronic neck pain.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.