Clinical trial Recruiting at 1 site Interventional Ages 18 to 45

Post Isometric Relaxation vs Reciprocal Inhibition for Cervicogenic Headache

Official title: Comparative Effects of Post Isometric Relaxation and Reciprocal Inhibition in Individuals With Cervicogenic Headache.

Run by Foundation University Islamabad · NCT07838545 · Data updated 2026-11-12

This study tests whether two gentle neck muscle techniques, post isometric relaxation and reciprocal inhibition, help people with cervicogenic headache more than a standard physical therapy routine.

Quick facts

Study typeInterventional
Ages18 Years to 45 Years
SexAll
Enrollment46 (estimated)
SponsorFoundation University Islamabad
Academic / other
Locations1 site (Islamabad, Punjab Province)
StatusRecruiting
StartedFebruary 12, 2026
Main results expectedDecember 18, 2026
Study endsJanuary 18, 2027
Registry record updatedSeptember 24, 2026
Trial IDNCT07838545 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18-45 with unilateral CGH lasting more than 3 months, restricted upper cervical mobility, and a positive cervical flexion-rotation test.

Probably not a fit

Individuals without significant cervical mobility restriction or those whose headaches are not primarily neck-related may experience little to no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial compares Post Isometric Relaxation (PIR) with Reciprocal Inhibition (RI) in adults 18-45 with cervicogenic headache. All participants receive a standard physiotherapy program including hot packs, neck isometrics, and C1-C2 SNAGs, three times weekly for four weeks. The trial aims to see which technique more effectively reduces pain, improves neck range of motion, and reduces functional disability associated with CGH. Participants are diagnosed per ICH criteria and have unilateral neck pain provoked by movement or sustained postures with restricted upper cervical mobility. Exclusion criteria include prior neck trauma, neoplasms, cognitive disorders, certain musculoskeletal conditions, other chronic pain syndromes, and recent cervical spine surgery.

Why it matters

Potential benefit: If successful, the technique found to be superior could become a preferred, non-pharmacologic option to reduce pain and improve function in cervicogenic headache.

How similar studies have gone: Previous studies have explored muscle energy techniques for neck-related headaches with mixed but promising results; this direct comparison in CGH is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria

* Patients are diagnosed according to ICH criteria.
* Age 18-45 years.
* Both Genders (Male and Female).
* Headache \> 3 months.
* Unilateral neck pain and associated headache.
* Headache is precipitated by neck movements or sustained positions.
* Restricted upper cervical segmental mobility.
* Positive cervical flexion rotation test, restriction greater than 10°.

Exclusion criteria

* History of head and neck trauma.
* Neoplasm.
* Cognitive disability.
* Inherited disorders such as scoliosis and torticollis.
* Other chronic pain syndrome (i.e.: fibromyalgia, systematic inflammatory disease).
* History of recent surgery of cervical spine.

Where it's running

  • Foundation University College of Physical Therapy
    Islamabad, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.