Clinical trial Recruiting at 1 site Interventional Ages 20 to 40 Women only

Physical activity program for women with PCOS and fatty pancreas plus subclinical hypothyroidism

Official title: Efficay of Physical Activity Program in PCOS Females With Fatty Pancrease and Thyroid Hypofunction

Run by Cairo University · NCT07591246 · Data updated 2026-11-12

A program of exercise is being tested to see if it helps women with PCOS who also have fatty pancreas and subclinical hypothyroidism, compared to usual care.

More Polycystic Ovary Syndrome trials

Quick facts

Study typeInterventional
Ages20 Years to 40 Years
SexWomen only
Enrollment40 (estimated)
SponsorCairo University
Academic / other
Locations1 site (Giza)
StatusRecruiting
StartedMarch 7, 2026
Main results expectedDecember 30, 2026
Study endsDecember 30, 2026
Registry record updatedMay 15, 2026
Trial IDNCT07591246 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are women with PCOS who also have non-alcoholic fatty pancreatic disease and subclinical hypothyroidism, not currently with active heart, kidney, or lung disease.

Probably not a fit

Patients with significant comorbidities or those unable to participate in an aerobic exercise program may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study targets women with polycystic ovary syndrome who also have fatty pancreatic disease and subclinical hypothyroidism. Participants are assigned to groups where one group receives a physical activity program in addition to usual care, while another group receives usual care alone or with standard medications. The exercise involves an aerobic treadmill walking component. Levothyroxine and metformin are used in the design to address thyroid function and insulin resistance, respectively. The trial is conducted at Cairo University and aims to explore whether adding structured physical activity can improve metabolic and endocrine parameters in this specific comorbidity profile.

Why it matters

Potential benefit: If successful, the program could improve metabolism and thyroid-related symptoms in women with PCOS and fatty pancreas.

How similar studies have gone: There is limited published evidence on combining aerobic exercise with this specific constellation of PCOS, fatty pancreas, and subclinical hypothyroidism; the approach is exploratory.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* PCOS
* fattty pancrease (non-alcoholic)
* subclinical hypothyroid (signifcant with thyroid stimauted horomone more than 10 mIU/L) and normal non-disordered free thyroxine horomones

Exclusion Criteria:

* cardiac disesase
* renal diseases
* respiratory disease

Where it's running

  • Cairo Unoversity
    Giza, Egypt
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.