Physical activity program for women with PCOS and fatty pancreas plus subclinical hypothyroidism
Official title: Efficay of Physical Activity Program in PCOS Females With Fatty Pancrease and Thyroid Hypofunction
Run by Cairo University · NCT07591246 · Data updated 2026-11-12
A program of exercise is being tested to see if it helps women with PCOS who also have fatty pancreas and subclinical hypothyroidism, compared to usual care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 40 Years |
| Sex | Women only |
| Enrollment | 40 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Giza) |
| Status | Recruiting |
| Started | March 7, 2026 |
| Main results expected | December 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | May 15, 2026 |
| Trial ID | NCT07591246 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are women with PCOS who also have non-alcoholic fatty pancreatic disease and subclinical hypothyroidism, not currently with active heart, kidney, or lung disease.
✕Probably not a fit
Patients with significant comorbidities or those unable to participate in an aerobic exercise program may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study targets women with polycystic ovary syndrome who also have fatty pancreatic disease and subclinical hypothyroidism. Participants are assigned to groups where one group receives a physical activity program in addition to usual care, while another group receives usual care alone or with standard medications. The exercise involves an aerobic treadmill walking component. Levothyroxine and metformin are used in the design to address thyroid function and insulin resistance, respectively. The trial is conducted at Cairo University and aims to explore whether adding structured physical activity can improve metabolic and endocrine parameters in this specific comorbidity profile.
Why it matters
Potential benefit: If successful, the program could improve metabolism and thyroid-related symptoms in women with PCOS and fatty pancreas.
How similar studies have gone: There is limited published evidence on combining aerobic exercise with this specific constellation of PCOS, fatty pancreas, and subclinical hypothyroidism; the approach is exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * PCOS * fattty pancrease (non-alcoholic) * subclinical hypothyroid (signifcant with thyroid stimauted horomone more than 10 mIU/L) and normal non-disordered free thyroxine horomones Exclusion Criteria: * cardiac disesase * renal diseases * respiratory disease
Where it's running
-
Cairo Unoversity
Giza, Egypt Recruiting
Study contacts
- Principal investigator: Ali MA Ismail, lecturer — Cairo University
- Study coordinator: Ali MA Ismail, lecturer
- Email: ali.mohamed@pt.cu.edu.eg
- Phone: 01005154209
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.