Glucose monitoring in women with polycystic ovary syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The project uses continuous glucose monitoring to characterize daily glucose patterns in adult women diagnosed with PCOS and to compare these patterns across the four recognized PCOS phenotypes (A–D). Participants will be classified by reproductive and biochemical features (menstrual irregularity, hyperandrogenism, ovarian morphology or AMH levels) and will wear a FreeStyle Libre Pro sensor to collect interstitial glucose readings over the monitoring period. Investigators will analyze glucose parameters such as mean glucose, time-in-range, glycemic variability, and episodes of hyperglycemia, and will compare these metrics between phenotypes while accounting for factors like insulin resistance and BMI. The aim is to determine whether certain PCOS phenotypes have worse glucose profiles that warrant closer metabolic surveillance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \> 18 years at inclusion criteria
* Patient with polycystic ovary syndrome, defined by the presence of at least 2/3 irregular menstrual cycles, clinical or biological hyperandrogenism, polycystic ovary morphology (pelvic ultrasound) or elevated AMH levels, after the exclusion of other disorders.
* Agreed to carry the FSL pro
* Signed informed consent

Exclusion Criteria:

* Pregnancy, breast-feeding
* Differential diagnoses: hyperprolactinemia, dysthyroidism, Cushing's syndrome, congenital adrenal hyperplasia, virilizing tumor (ovarian or adrenal), intake of exogenous androgens
* Pre-existing diabetes
* Patient treated within 3 months prior to inclusion/data collection with estrogen-progestin contraception, progestin contraception, antidiabetic drugs, inositol, antiandrogen

Where it's running

• CHRU Amiens
  Salouël, France Recruiting

Study contacts

• Study coordinator: Abdallah Al-Salameh, Pr
• Email: Al-Salameh.Abdallah@chu-amiens.fr
• Phone: 33+3.22.08.83.71

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Investigating mitochondrial dysfunction in women with PCOS and infertility

  This study is trying to see if problems with energy production in cells are linked to polycystic ovary syndrome (PCOS) and infertility in women.

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• Investigating fasting insulin and insulin resistance across different demographics

  This study looks at how fasting insulin levels and insulin resistance vary among different groups of people based on age, sex, race, weight, and conditions like PCOS to better understand metabolic health.

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• Asprosin and miRNA Profiles in Young Women with Metabolic Syndrome

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  Recruiting University of Applied Sciences in Nowy Targ · Nowy Targ, Lesser Poland Voivodeship · NCT07917364

• Precision acupuncture and lifestyle for PCOS

  This trial tests whether a precision acupuncture approach combined with a personalized lifestyle plan helps improve insulin resistance in people with PCOS compared with conventional acupuncture and standard lifestyle changes.

  Recruiting Peking University Third Hospital · Beijing, Beijing Municipality and 1 other locations · NCT07809503

• Prenatal Exercise to See How Cardio or Strength Training Affects Blood Sugar

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• Alpelisib Challenge Test to measure insulin secretory capacity

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  Recruiting Phase 1 Columbia University · New York, New York · NCT07778524

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.