Personalized virtual speech therapy to improve communication in primary progressive aphasia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional telerehabilitation program delivers two targeted speech-language approaches (lexical retrieval cascade training and video-implemented script training) via virtual sessions to adults with PPA and their primary communication partners. Participants who receive immediate treatment are compared with a waitlist control group who receive the same program after a delay. The study enrolls English- and/or Spanish-speaking participants with milder-to-moderate PPA who have a study partner and adequate hearing/vision for teleconferencing. Outcomes include measures of feasibility and acceptability, communication performance, partner-reported benefit, and patterns of treatment response to determine which measures best capture change.

Why it matters

Who can join: the full rules

Inclusion Criteria for Persons with PPA:

* A PPA (Gorno-Tempini et al., 2011) or "PPA-plus" (Mesulam et al., 2001) diagnosis
* MMSE score of 15 or higher and must be able to produce single monosyllabic words intelligibly
* Must speak English, Spanish or both languages (i.e., bilingual speakers of English or Spanish)
* Hearing and vision adequate for participation in teleconference meetings
* Must have a study partner available (someone who will commit to attending teleconference sessions, as needed, during assessment and treatment phases)

Inclusion criteria for Care Partners:

* Partners must express willingness to attend and participate in assessment and treatment sessions, including those targeting dyadic communication goals
* Partners must speak English, Spanish or both languages (i.e., bilingual speakers of English or Spanish)
* Partner's hearing and vision should be adequate for participation in teleconference meetings

The participant and/or study partner must have basic experience using a computer.

Exclusion criteria for persons with PPA:

* Other central nervous system or medical diagnosis that can account for symptoms
* Psychiatric diagnosis that can account for symptoms

Where it's running

• University of Texas
  Austin, Texas, United States Recruiting

Study contacts

• Principal investigator: Maya L Henry, PhD — University of Texas at Austin
• Study coordinator: Henry Lab Research Coordinator
• Email: aphasialab@austin.utexas.edu
• Phone: 512-471-3420

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Educational support program for bilingual individuals with progressive aphasia and their caregivers

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.