Condition
Primary Progressive Aphasia(PPA) clinical trials and research
As of November 12, 2026, Find a Trial lists 5 Primary Progressive Aphasia(PPA) clinical trials that are recruiting, at sites in 3 countries (most in United States (3), Italy (1), Spain (1)). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 5Clinical trials
- 3Countries
Newest Primary Progressive Aphasia(PPA) clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Home-based brain stimulation with virtual speech therapy for logopenic PPA | — | San Francisco, California and 1 other locations | Recruiting | Dec 3, 2025 |
| Personalized virtual speech therapy to improve communication in primary progressive aphasia | — | Austin, Texas | Recruiting | Oct 22, 2025 |
| Long-term brain stimulation for primary progressive aphasia | — | Madrid | Recruiting | Sep 5, 2025 |
| Speech and language therapy for Italian patients with primary progressive aphasia | — | Bari and 1 other locations | Recruiting | Dec 18, 2024 |
| Creating a repository for neurodegenerative disease data | — | Philadelphia, Pennsylvania | Recruiting | Jan 20, 2021 |
All recruiting trials (5)
-
Home-based brain stimulation with virtual speech therapy for logopenic PPA
This project will test whether home-based transcranial direct current stimulation (tDCS) combined with virtual speech-language therapy helps people with the logopenic variant of primary progressive aphasia communicate better.
-
Personalized virtual speech therapy to improve communication in primary progressive aphasia
This project tests whether a tailored, multi-part virtual speech-language program can help adults with primary progressive aphasia and their communication partners communicate better and improve quality of life.
-
Long-term brain stimulation for primary progressive aphasia
This trial will test whether two non-invasive brain stimulation methods (TMS and tDCS), alone or combined and paired with language therapy, can slow or improve language decline over six months in people with primary progressive aphasia.
-
Speech and language therapy for Italian patients with primary progressive aphasia
This study is testing whether speech and language therapy can help Italian patients with primary progressive aphasia improve their communication skills and feel more satisfied with their progress.
-
Creating a repository for neurodegenerative disease data
This study is creating a large collection of information about neurodegenerative diseases to help researchers learn more and develop better treatments for people affected by these conditions.
Related topics
Quick answers
How many Primary Progressive Aphasia(PPA) clinical trials are recruiting right now?
5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 3 countries. The most sites are in United States (3 trials), Italy (1 trial), Spain (1 trial). Each study page lists its sites and which ones are recruiting.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.