Optimizing treatment for idiopathic inflammatory myopathies
Optimizing Treatment on Idiopathic Inflammatory Myopathies
University of Sao Paulo · NCT03092180
This study is testing whether a combination of two treatments or just one can help people with idiopathic inflammatory myopathies feel better when they first start their treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Sao Paulo (other) |
| Locations | 1 site (São Paulo) |
| Trial ID | NCT03092180 on ClinicalTrials.gov |
What this trial studies
This observational study aims to optimize treatment for patients with idiopathic inflammatory myopathies by comparing two groups receiving different pulse therapies. Patients will either receive a combination of methylprednisolone and human intravenous immunoglobulin or just methylprednisolone at the onset of their disease. The study follows an internal routine protocol of the service at the University of Sao Paulo, focusing on the effectiveness of these treatment regimens.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with idiopathic inflammatory myopathies.
Not a fit: Patients with inclusion body myositis, muscular dystrophies, neoplasia-associated myopathies, overlapped myopathies, or other myopathies may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols for patients suffering from idiopathic inflammatory myopathies.
How similar studies have performed: Other studies have shown success with similar immunomodulatory approaches in treating inflammatory myopathies, suggesting potential for positive outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Idiopathic inflammatory myopathies Exclusion Criteria: * Inclusion body myositis, muscular dystrophies, neoplasia-associated myopathies, overlapped myopathies, others myopathies
Where this trial is running
São Paulo
- Samuel Katsuyuki Shinjo — São Paulo, Brazil (RECRUITING)
Study contacts
- Principal investigator: Samuel K Shinjo, PhD — Universidade de Sao Paulo - Rheumatology Division
- Study coordinator: Samuel K Shinjo, PhD
- Email: samuel.shinjo@gmail.com
- Phone: 55-11-3061-7176
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Idiopathic Inflammatory Myopathies, Dermatomyositis, Immunomodulation, Immunosuppressive agents, Myositis, Polymyositis, Necrotizing myopathies, Antisynthetase syndrome