Condition
Antisynthetase Syndrome clinical trials and research
As of November 12, 2026, Find a Trial lists 3 Antisynthetase Syndrome clinical trials that are recruiting, at sites in 2 countries (most in China (2), United States (1)). By phase: Early Phase 1 (1), Phase 2 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 3Clinical trials
- 2Countries
Newest Antisynthetase Syndrome clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| JAK inhibitors versus calcineurin inhibitors as initial therapy for antisynthetase syndrome–associated ILD | — | Beijing, Beijing Municipality | Recruiting | Feb 12, 2026 |
| Descartes-08 for autoantibody myositis (antisynthetase syndrome and dermatomyositis) | Phase 2 | Orange, California and 3 other locations | Recruiting | Feb 6, 2026 |
| Using CD19 CAR NK cells to treat refractory antisynthetase antibody syndrome and rheumatoid arthritis | Early Phase 1 | Nanjing, Jiangsu | Recruiting | Sep 26, 2024 |
All recruiting trials (3)
-
JAK inhibitors versus calcineurin inhibitors as initial therapy for antisynthetase syndrome–associated ILD
This trial tests whether a JAK inhibitor or a calcineurin inhibitor, given with steroids, works better as the first treatment for antisynthetase syndrome–related interstitial lung disease in adults who haven’t been treated yet.
-
Descartes-08 for autoantibody myositis (antisynthetase syndrome and dermatomyositis)
This trial will test whether Descartes-08, an mRNA CAR-T therapy targeting BCMA, can help adults with autoantibody-driven myositis such as antisynthetase syndrome or dermatomyositis who have not responded to standard treatments.
-
Using CD19 CAR NK cells to treat refractory antisynthetase antibody syndrome and rheumatoid arthritis
This study tests if a new treatment using special immune cells can help people with tough cases of antisynthetase antibody syndrome and rheumatoid arthritis feel better.
Related topics
Quick answers
How many Antisynthetase Syndrome clinical trials are recruiting right now?
3, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in China (2 trials), United States (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Early Phase 1: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.