Optimizing MRI protocols for better diagnostic quality
Official title: OSV-IRM - Volunteer MRI Sequence Optimization
Run by Rennes University Hospital · NCT05107232 · Data updated 2026-11-12
This study is trying out different MRI techniques to see if they can improve the quality of images for both healthy people and patients who need scans.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 6 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Rennes University Hospital Academic / other |
| Locations | 1 site (Rennes) |
| Status | Recruiting |
| Started | November 4, 2021 |
| Main results expected | November 2026 |
| Study ends | December 2027 |
| Registry record updated | November 12, 2021 |
| Trial ID | NCT05107232 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include healthy volunteers without relevant medical history and patients who have a medical indication for an MRI exam.
✕Probably not a fit
Patients with contraindications to MRI or those under legal protection measures may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on optimizing magnetic resonance imaging (MRI) protocols by testing various technical parameters on both healthy volunteers and patients requiring MRI scans. Participants will undergo an inclusion visit to verify eligibility, followed by an imaging visit for the MRI examination, which can occur on the same day or within 15 days. The study is conducted at Rennes University Hospital and aims to enhance the diagnostic quality of MRI through tailored protocols.
Why it matters
Potential benefit: If successful, this study could lead to improved MRI diagnostic quality, benefiting patients with more accurate imaging results.
How similar studies have gone: While there have been studies focusing on MRI optimization, this specific approach may offer novel insights into protocol enhancements.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Criteria common to all participants: * Minor or major subject * Affiliated, himself or through his parents if he is a minor, to a a social security scheme * Having given their free, informed and written consent, and/or which the free, informed and written consent of the holder(s) parental authority has been obtained for minors Specific criteria for healthy volunteers: o No medical or surgical history related to the anatomical area(s) scanned Specific criteria for voluntary patients: o Indication for an MRI exam as part of its management Exclusion Criteria: * \- Contraindication to an MRI (pacemaker or pacemaker, neurostimulator, intra-orbital metal body, vascular clip ferromagnetic) * Pregnancy * Legal protection measure for adults in progress (safeguard of justice, guardianship, curatorship) or subject deprived of liberty
Where it's running
-
CHU Rennes
Rennes, France Recruiting
Study contacts
- Principal investigator: Jean-Christophe FERRE, Pr — Rennes University Hospital
- Study coordinator: Blandine Gautier
- Email: blandine.gautier@chu-rennes.fr
- Phone: 299282591
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
12-week ETAS® supplement for thinking, mood, sleep, and brain health in older adults
This 12-week test will see if taking 1500 mg ETAS® daily helps thinking, mood, sleep, and brain scan measures in healthy adults aged 60–80 with mild cognitive complaints.
-
MRI versus ultrasound for early liver cancer detection, body composition, and decompensation risk in cirrhosis
This project will test whether abbreviated MRI or ultrasound is better at finding early liver cancer and measuring muscle and fat in adults with cirrhosis.
-
Using breath-hold methods with and without oxygen to improve liver MRI image quality
This study will test whether holding your breath at end-expiration, with or without extra oxygen, improves abdominal MRI image quality in healthy adults ages 18–75.
-
Cortical Excitability and DLPFC Structure in Healthy Adults Using TMS, EEG, and High-Field MRI
This study tests how reproducible brain signals from transcranial magnetic stimulation relate to the anatomy of the left prefrontal cortex in healthy adults.
-
Early care pathway for knee sprains using automated dynamic laximetry
This test tries using automated dynamic laximetry (ADL) right after an ER visit instead of immediate MRI to diagnose suspected ACL tears in adults with knee sprain.
-
Examining MRI Features to Improve Prostate Cancer Diagnosis
This study is trying to see if special MRI pictures can help doctors better diagnose prostate cancer in men with high PSA levels or abnormal exams, aiming to reduce unnecessary biopsies and improve patient care.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.