Older adults with viral lung infections: how common viruses show up in hospital patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study is a prospective, multicenter observational effort enrolling hospitalized patients aged 60+ who have a respiratory sample tested for viruses with PCR. Each participant is followed for 3 months after discharge, with data collected from standard-of-care testing and local virology labs. About 20 centers over 24 months will contribute data to describe the viral causes of SARIs in older adults and related clinical features.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Hospitalized subjects aged ≥ 60 years
* A respiratory sample collected and tested by polymerase chain reaction (PCR) during hospitalisation as part of standard of care

Note: Reasons for PCR:

1. Patients with Severe acute respiratory infection (SARI)
2. Patients with symptoms other than SARI
3. Systematic PCR testing (in the context of clusters or during the winter season) \* Recent onset of at least one general symptom and at least one functional or physical respiratory sign

   * General symptoms: fever (which may be absent in older patients), chills, sweating, headache, malaise, myalgia, arthralgia, fatigue, decline in general condition (asthenia, weight loss, anorexia, confusion, or dizziness), digestive disturbances.
   * Respiratory signs: sore throat, rhinorrhoea (common cold), cough, wheezing, dyspnoea, chest pain, or recent auscultatory abnormalities (diffuse or focal).
   * Subjects willing to participate, with a non-opposition form completed and signed by the qualified and trained healthcare professional responsible for providing the participant information
   * Subject affiliated to a health insurance system

Exclusion Criteria:

* Subjects refusing to participate
* Subjects admitted to palliative care unit.

  * Subjects under guardianship
  * Any condition that, in the opinion of the investigator, may interfere with the aim of the study or wellbeing of the patient

Where it's running

• Centre Hospitalier Départemental Vendée_La Roche sur Yon
  La Roche-sur-Yon, France Recruiting
• Hôpital Broca - APHP
  Paris, France Recruiting
• Hôpital Avicenne APHP
  Bobigny, Île-de-France Region, France Recruiting
• Hôpital Corentin Celton APHP, Gérontologie 2
  Issy-les-Moulineaux, Île-de-France Region, France Recruiting
• Hôpital Emile Roux APHP
  Limeil-Brévannes, Île-de-France Region, France Recruiting
• CHU Bordeaux
  Pessac, Bordeaux, France Not yet recruiting

Study contacts

• Study coordinator: Isabelle Dufour
• Email: isabelle.dufour@gerondif.org
• Phone: +33 (0) 185781011

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.