Observing pneumonia and pleural effusion in hospitalized children
Official title: French Epidemiological Pediatric Study for Pneumonia and Pleuropneumonia in Hospitalized Children Aged 1 Months to 15 Years.
Run by Association Clinique Thérapeutique Infantile du val de Marne · NCT05274607 · Data updated 2026-11-12
This study looks at how common pneumonia and fluid around the lungs are in hospitalized children to understand the causes, symptoms, and how well treatments work.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Month to 15 Years |
| Sex | All |
| Enrollment | 20000 (estimated) |
| Sponsor | Association Clinique Thérapeutique Infantile du val de Marne Academic / other |
| Locations | 1 site (Créteil) |
| Status | Recruiting |
| Started | June 1, 2009 |
| Main results expected | December 1, 2029 |
| Study ends | December 1, 2029 |
| Registry record updated | October 27, 2026 |
| Trial ID | NCT05274607 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children aged 1 month to 15 years who are hospitalized with pneumonia or pleural effusion.
✕Probably not a fit
Patients who do not require hospitalization or refuse participation will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to describe the epidemiology of hospitalized pediatric pneumonia and pneumonia with pleural effusion, focusing on frequency, clinical characteristics, responsible bacteria, and antibiotic resistance. It includes data from over 15,000 children since 2009, with a recent shift to only include hospitalized cases to better understand severe instances. The study will analyze the long-term impact of the pneumococcal conjugate vaccine on these conditions. Data collection will involve reviewing chest imaging and clinical symptoms to assess the severity and treatment outcomes.
Why it matters
Potential benefit: If successful, this study could enhance understanding of severe pneumonia in children and improve treatment strategies.
How similar studies have gone: Previous studies on pediatric pneumonia have shown success in understanding the disease, but this specific focus on hospitalized cases is a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ages between 1 month and 15 years * presence of parenchymatous condensation and/or pleural effusion on chest x-rays and/or ultrasounds and/or CT scans * fever ≥38.5 °C if age ≥3 months since the onset of symptoms or ≥38 °C if the child is less than 3 months old. * Hospitalization Exclusion Criteria: * Refusal of participation by the patient, his or her relative or legal representative (depending on the situation)
Where it's running
-
Activ
Créteil, France Recruiting
Study contacts
- Study coordinator: Corinne Levy, MD
- Email: corinne.levy@activ-france.fr
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.