Using portable dynamic chest X-ray in the ICU

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the feasibility and safety of a portable dynamic digital radiography (DDR) system in the ICU, which captures high-resolution images of lung motion, ventilation, and perfusion at a rate of 15 frames per second. Participants will receive one to three sets of DDR images that will be compared to traditional imaging methods like chest X-rays and CT scans to assess the diagnostic value of this new technology. The goal is to improve the precision and accuracy of lung assessments in critically ill patients.

Why it matters

Who can join: the full rules

Inclusion Criteria: Participants must meet all the following inclusion criteria to participate in this study:

* Adults (at least 18 years of age) including both intubated/ventilated and non-intubated patients
* Likely to have pathology related to either, abnormal diaphragmatic excursion and lung aeration, pulmonary perfusion, increased lung water content or all the above, as well as for cricopharyngeal dysfunction/swallowing difficulties at risk for aspiration.
* The subject or a legally authorized representative has provided written informed consent.

Exclusion Criteria: Candidates meeting any of the exclusion criteria at baseline will be excluded from study participation. These criteria are:

* Special populations, including women with known pregnancy, prisoners, or institutionalized individuals
* Patients where additional radiation is clinically contraindicated
* Care team does not provide assent for approaching patient/surrogate
* For women of child-bearing potential, defined as premenopausal women, a pregnancy test will be administered to determine pregnancy status and confirm eligibility for the study. A pregnancy test will NOT be administered to women who are post-menopausal or have documentation of surgical sterilization.

Where it's running

• Brigham and Women's Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Gyorgy Frendl, MD PhD — Brigham and Women's Hospital
• Study coordinator: Gyorgy Frendl, MD PhD
• Email: gfrendl@bwh.harvard.edu
• Phone: 617-732-5910

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.