Observing pediatric patients who have stopped using parenteral nutrition

Weaning is Winning? (WeWin Study): Are Parenteral Nutrition (PN) Graduates Growing Up Healthy?

Observational The Hospital for Sick Children · NCT06525753

This study looks at children who have stopped using parenteral nutrition to see what health issues they might face afterward and to find out which kids are most at risk.

Quick facts

Study typeObservational
Enrollment120 (estimated)
Ages0 Years to 18 Years
SexAll
SponsorThe Hospital for Sick Children Academic / other
Locations1 site (Toronto, Ontario)
Trial IDNCT06525753 on ClinicalTrials.gov

What this trial studies

This multicenter prospective study focuses on pediatric patients with intestinal failure who have successfully weaned off parenteral nutrition. The research aims to assess the frequency and types of complications that may arise after discontinuing parenteral nutrition, as well as identifying which patients are at the highest risk for these complications. By gathering data on these patients, the study seeks to improve understanding of post-weaning health outcomes and quality of life. The study will involve monitoring these patients over time to gather comprehensive data on their health status.

Who should consider this trial

Good fit: Ideal candidates are pediatric patients under 18 years old who have been off parenteral nutrition for at least one year and have a history of intestinal failure.

Not a fit: Patients who do not provide consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the management and quality of life for pediatric patients who have transitioned off parenteral nutrition.

How similar studies have performed: While there have been studies on complications related to parenteral nutrition, this specific focus on post-weaning outcomes in pediatric patients is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Parenteral Nutrition graduates for at least 1 year, with a history of intestinal failure.
* Age \<18 years at time of inclusion.

Exclusion criteria:

* No consent provided.

Where this trial is running

Toronto, Ontario

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Intestinal FailureParenteral NutritionQuality of LifePediatric
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.