Observing long-term changes in high myopia patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to track the long-term changes in ocular structure and visual function in individuals with high myopia, defined as a refractive error of ≤-6.00D or an axial length greater than 26mm. The study will involve a cohort of 1000 participants, primarily college students, over a four-year period, utilizing advanced imaging technologies such as optical coherence tomography (OCT) to gather data on fundus structure and visual function. The goal is to identify biomarkers that may influence visual outcomes and provide insights for the prevention and management of high myopia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Voluntarily sign informed consent;
* Commit to follow the research procedures and cooperate with the whole process of the study;
* Age ≥18 years old;
* Best corrected visual acuity ≥0.1;
* Spherical Equivalent Refraction≤-6.00D or axial length ≥26mm in high myopia group；

Exclusion Criteria:

* Unable or unwilling to sign informed consent;
* Unable to cooperate with the examination;
* Astigmatism ≤-1.5D；
* Patients with refractive interstitial opacity so that fundus images cannot be collected；
* Patients with fundus diseases such as diabetic retinopathy, hypertensive retinopathy, age-related macular degeneration, retinal vein obstruction, retinal artery obstruction, etc

Where it's running

• Renmin Hospital of Wuhan University
  Wuhan, Hubei, China Recruiting

Study contacts

• Study coordinator: QY Wu, MD
• Email: wuqyan@163.com
• Phone: +86 18672345926

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.