Evaluating long-term visual outcomes after cataract surgery in high myopia patients
Visual Outcome Evaluation and Genetic Analysis: Shanghai High Myopia Study
This study looks at how cataract surgery affects vision over time in people with severe nearsightedness compared to those with regular age-related cataracts.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60000 (estimated) |
| Ages | 20 Years to 100 Years |
| Sex | All |
| Sponsor | Shanghai High Myopia Study Group Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Trial ID | NCT03062085 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the long-term visual outcomes of cataract surgery in patients with high myopic cataracts compared to age-related cataract patients. It utilizes a large-scale database to analyze various genetic and environmental factors contributing to high myopic cataract pathogenesis. The study will focus on identifying specific genes associated with the condition and its complications, ultimately aiming to establish a risk model for high myopic cataract through precision medicine. The findings could enhance understanding and treatment strategies for this prevalent condition in China.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with cataracts, particularly those with high myopia.
Not a fit: Patients with mental illnesses or disabilities that prevent cooperation with ophthalmic examinations may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and personalized treatment strategies for patients with high myopic cataracts.
How similar studies have performed: Previous studies have indicated a lack of extensive research on high myopic cataracts, making this approach novel and potentially groundbreaking.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of cataract * Must be able to cooperate with the ophthalmic examination Exclusion Criteria: * Clinical diagnosis of mental illness * Mentally disabled
Where this trial is running
Shanghai, Shanghai Municipality
- Eye and ENT Hospital of Fudan University — Shanghai, Shanghai Municipality, China (Recruiting)
Study contacts
- Principal investigator: Keke Zhang, M.D. — Eye and ENT Hospital of Fudan University
- Study coordinator: Yi Lu, M.D.
- Email: luyieent@163.com
- Phone: (86)021-64377134
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.