Evaluating long-term visual outcomes after cataract surgery in high myopia patients
Official title: Visual Outcome Evaluation and Genetic Analysis: Shanghai High Myopia Study
Run by Shanghai High Myopia Study Group · NCT03062085 · Data updated 2026-11-12
This study looks at how cataract surgery affects vision over time in people with severe nearsightedness compared to those with regular age-related cataracts.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 20 Years to 100 Years |
| Sex | All |
| Enrollment | 60000 (estimated) |
| Sponsor | Shanghai High Myopia Study Group Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | January 1, 2015 |
| Main results expected | December 31, 2035 |
| Study ends | December 31, 2045 |
| Registry record updated | May 11, 2026 |
| Trial ID | NCT03062085 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with cataracts, particularly those with high myopia.
✕Probably not a fit
Patients with mental illnesses or disabilities that prevent cooperation with ophthalmic examinations may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the long-term visual outcomes of cataract surgery in patients with high myopic cataracts compared to age-related cataract patients. It utilizes a large-scale database to analyze various genetic and environmental factors contributing to high myopic cataract pathogenesis. The study will focus on identifying specific genes associated with the condition and its complications, ultimately aiming to establish a risk model for high myopic cataract through precision medicine. The findings could enhance understanding and treatment strategies for this prevalent condition in China.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and personalized treatment strategies for patients with high myopic cataracts.
How similar studies have gone: Previous studies have indicated a lack of extensive research on high myopic cataracts, making this approach novel and potentially groundbreaking.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of cataract * Must be able to cooperate with the ophthalmic examination Exclusion Criteria: * Clinical diagnosis of mental illness * Mentally disabled
Where it's running
-
Eye and ENT Hospital of Fudan University
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Principal investigator: Keke Zhang, M.D. — Eye & ENT Hospital of Fudan University
- Study coordinator: Yi Lu, M.D.
- Email: luyieent@163.com
- Phone: (86)021-64377134
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Capsular tension ring to improve intraocular lens stability in people with high myopia and cataracts
This test will see if placing a capsular tension ring in one eye during cataract surgery helps the artificial lens stay centered and gives better vision for people with high myopia, by comparing the treated eye to the other eye without the ring.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.