Clinical trial Recruiting at 1 site Observational Ages 20 to 100

Evaluating long-term visual outcomes after cataract surgery in high myopia patients

Official title: Visual Outcome Evaluation and Genetic Analysis: Shanghai High Myopia Study

Run by Shanghai High Myopia Study Group · NCT03062085 · Data updated 2026-11-12

This study looks at how cataract surgery affects vision over time in people with severe nearsightedness compared to those with regular age-related cataracts.

Quick facts

Study typeObservational
Ages20 Years to 100 Years
SexAll
Enrollment60000 (estimated)
SponsorShanghai High Myopia Study Group
Academic / other
Locations1 site (Shanghai, Shanghai Municipality)
StatusRecruiting
StartedJanuary 1, 2015
Main results expectedDecember 31, 2035
Study endsDecember 31, 2045
Registry record updatedMay 11, 2026
Trial IDNCT03062085 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals diagnosed with cataracts, particularly those with high myopia.

Probably not a fit

Patients with mental illnesses or disabilities that prevent cooperation with ophthalmic examinations may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the long-term visual outcomes of cataract surgery in patients with high myopic cataracts compared to age-related cataract patients. It utilizes a large-scale database to analyze various genetic and environmental factors contributing to high myopic cataract pathogenesis. The study will focus on identifying specific genes associated with the condition and its complications, ultimately aiming to establish a risk model for high myopic cataract through precision medicine. The findings could enhance understanding and treatment strategies for this prevalent condition in China.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and personalized treatment strategies for patients with high myopic cataracts.

How similar studies have gone: Previous studies have indicated a lack of extensive research on high myopic cataracts, making this approach novel and potentially groundbreaking.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical diagnosis of cataract
* Must be able to cooperate with the ophthalmic examination

Exclusion Criteria:

* Clinical diagnosis of mental illness
* Mentally disabled

Where it's running

  • Eye and ENT Hospital of Fudan University
    Shanghai, Shanghai Municipality, China
    Recruiting

Study contacts

  • Principal investigator: Keke Zhang, M.D. — Eye & ENT Hospital of Fudan University
  • Study coordinator: Yi Lu, M.D.
  • Email: luyieent@163.com
  • Phone: (86)021-64377134

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.