Minimally invasive surgery for patients with impaired lung function

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates a non-intubated minimally invasive surgical approach for patients with impaired lung function who require surgical treatment for conditions such as lung cancer and pneumothorax. The method allows patients to maintain spontaneous breathing during the procedure, potentially reducing the need for postoperative intubation and ICU transfer. By avoiding endotracheal intubation, the trial aims to decrease the risks of airway injury and respiratory failure, thereby improving recovery outcomes. The study involves thorough preoperative assessments and multidisciplinary team discussions to ensure patient safety and suitability for the procedure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with impaired lung function (who may require postoperative intubation and transfer to the surgical ICU after preoperative and MDT discussions).
2. Patients requiring minimally invasive lung resection due to lung cancer, pulmonary nodules, benign lung tumors, pneumothorax, lung volume reduction surgery, etc.
3. Patients with normal mental status who can cooperate with perioperative examinations, exercises, and physical rehabilitation measures.
4. Patients who agree to participate in the clinical trial after communication.

Exclusion Criteria:

1. Patients with severe impairment of cardiopulmonary function or other organ systems, who are deemed unable to tolerate any form of anesthesia or minimally invasive surgery after preoperative and MDT discussions.
2. Patients with abnormal mental status or who are unable to adequately cooperate with perioperative examinations, exercises, and physical rehabilitation measures.
3. Patients who refuse to participate in the clinical trial or decline the use of non-intubated anesthesia with preserved spontaneous breathing.
4. Patients who refuse to undergo surgery.

Where it's running

• The Second Hospital of Shandong University
  Jinan, Shandong, China Recruiting

Study contacts

• Principal investigator: Yunpeng Zhao — The Second Hospital of Shandong University
• Study coordinator: Yunpeng Zhao
• Email: zhaoyunpengsddx@sdu.edu.cn
• Phone: 18766188692

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Evaluating breathing difficulties using exercise testing and oscillometry

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• SPECT-guided radiation that spares well-functioning lung during curative lung cancer treatment

  This trial will test whether using perfusion SPECT/CT to guide radiation plans that avoid highly functional lung reduces radiation-related lung damage for adults receiving curative chemo-radiation for lung cancer.

  Recruiting at 2 sites University of Aarhus · Sydney, New South Wales and 1 other locations · NCT04676828

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.