Observational study on nummular headache treatments and outcomes

Nummular Headache Iberian Study on the Treatments and Outcomes in Real-World Setting

Observational Hospital Clínico Universitario de Valladolid · NCT05475769

This study is testing different preventive treatments for nummular headache to see how well they work and how patients tolerate them.

Quick facts

Study typeObservational
Enrollment98 (estimated)
Ages18 Years and up
SexAll
SponsorHospital Clínico Universitario de Valladolid Academic / other
Locations1 site (Valladolid)
Trial IDNCT05475769 on ClinicalTrials.gov

What this trial studies

The NUMITOR study is an analytical observational study designed to create a multicenter registry focused on nummular headache. It employs a cohort design that includes both retrospective and prospective data collection. The study aims to enhance understanding of nummular headache and evaluate the effectiveness and tolerability of various preventive treatments as determined by neurologists. Participants will be patients diagnosed with nummular headache who require preventive treatment, whether oral or injectable.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old with a diagnosis of nummular headache lasting more than three months.

Not a fit: Patients whose headaches are better explained by other conditions or who have serious systemic or psychiatric issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into effective treatment options for patients suffering from nummular headache.

How similar studies have performed: While there may be studies on headache disorders, this specific focus on nummular headache treatments is relatively novel and underexplored.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Nummular headache according to the criteria of the International Classification of Headache Disorders, third version (ICHD-3).
2. Nummular headache duration of more than three months.
3. Treatment with a medication with possible preventive drug according to the Clinical Practice Guidelines of the Spanish Society of Neurology21.
4. Age over 18 years.
5. Informed consent signature.

Exclusion Criteria:

1. Diagnosis is better accounted for by any other entity included in the International Classification of Headache Disorders, 3rd version.
2. Serious systemic or psychiatric pathology that makes it difficult to assess the patient.
3. Secondary nummular headache
4. Use of preventive treatment with another indication (e.g., epilepsy, other painful conditions, aesthetic).

Where this trial is running

Valladolid

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Headache Disorders, SecondaryHeadache DisordersCentral Nervous System DiseasesBrain DiseasesNeurologic ManifestationsNervous System DiseasesPain
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.