Non-surgical periodontal treatment in periodontitis patients using MINST or quadrant-wise Q-SI

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Sixty adults with periodontitis are randomly assigned in a double-blind design to receive minimally invasive non-surgical periodontal treatment via MINST or quadrant-wise Q-SI. Measurements of clinical and periodontal outcomes, plus gingival crevicular fluid metabolites, are taken before and after initial treatment. The trial focuses on how these treatments affect targeted metabolomics in the gum fluid while monitoring standard periodontal health indicators. Probing depth reduction is the primary intervention outcome. The study is conducted at AOU Policlinico G. Rodolico in Catania, Italy, with University of Catania as lead sponsor.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of Periodontitis

Exclusion Criteria:

* Periodontal treatment during the last 6 months
* Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months
* Pregnancy

Where it's running

• AOU Policlinico G. Rodolico
  Catania, Italy, Italy Recruiting

Study contacts

• Study coordinator: Gaetano Isola
• Email: gaetano.isola@unict.it
• Phone: 0953785652

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.