Non-contrast MRA vs Carotid Doppler for detecting carotid artery narrowing in stroke or TIA

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational study enrolls 200 adults with ischemic stroke or TIA to compare non-contrast magnetic resonance angiography (NC-MRA) and carotid Doppler ultrasonography for detecting and grading carotid stenosis using NASCET criteria. Each participant undergoes both imaging tests within 7–14 days of symptom onset, and results are analyzed for agreement and clinical utility. The goal is to determine how well NC-MRA performs relative to Doppler and to inform imaging strategies for cerebrovascular assessment. The study is conducted at Sohag University Hospital with Sohag University as the lead sponsor.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older.
* Clinically diagnosed ischemic stroke or transient ischemic attack (TIA).
* Imaging performed within 7-14 days of symptom onset.
* Hemodynamically stable and suitable for magnetic resonance imaging (MRI).
* Able and willing to provide written informed consent.

Exclusion Criteria:

* Hemorrhagic stroke.
* Previous carotid artery stenting.
* Contraindications to MRI, including:

  * Non-MRI-compatible pacemakers or other MRI-incompatible implants.
  * Cochlear implants.
  * MRI-incompatible metallic orthopedic implants.
  * Severe claustrophobia.

Where it's running

• Sohag University Hospital
  Sohag, Sohag Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Mohamed Saad Gad
• Email: mohsaadgad@gmail.com
• Phone: +201112435154

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals

  This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.

  Recruiting at 2 sites Hospital Universitari Vall d'Hebron Research Institute · Leuven and 6 other locations · NCT07924371

• Long-term follow-up after a year of regular exercise for people with symptomatic intracranial arterial stenosis

  This follow-up will see if benefits from a year of regular physical exercise last over three years for people with symptomatic intracranial arterial stenosis who completed the RESIST program.

  Recruiting Capital Medical University · Beijing · NCT07242768

• Using Ticagrelor to Adjust Antiplatelet Therapy for Ischemic Stroke

  This study is testing whether taking a lower dose of ticagrelor with aspirin for six months is better than a higher dose for one month in preventing more strokes in people who have had a non-disabling stroke or high-risk TIA.

  Recruiting Phase 2/3 Mazandaran University of Medical Sciences · Sari, Mazandaran · NCT06653348

• Using mobile technology to manage cardiovascular risks in stroke patients

  This study is testing if using mobile technology to monitor blood pressure and check for heart rhythm problems can help stroke patients manage their cardiovascular risks better than standard care.

  Recruiting at 4 sites Hospital District of Helsinki and Uusimaa · Hämeenlinna and 3 other locations · NCT03710902

• Remote ischemic conditioning for post-stroke insomnia

  A 136-person, randomized study will test whether a non-invasive arm-cuff procedure done twice daily for 90 days can improve sleep after a first ischemic stroke in adults 18–80.

  Recruiting Sichuan Academy of Medical Sciences · Chengdu, Sichuan · NCT07874594

• Ear-based nerve stimulation to help sleep after a stroke

  A device that delivers vagal nerve stimulation through the ear is tested to see if it helps stroke patients in rehab sleep better.

  Recruiting Casa Colina Hospital and Centers for Healthcare · Pomona, California · NCT07858656

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.