New diagnostic tools and treatments for endometriosis
Official title: Novel Diagnostic Tools for Endometriosis and Their Exploitation for Prognosis and Prevention of Complications
Run by Turku University Hospital · NCT01301885 · Data updated 2026-11-12
This study is trying out new ways to diagnose and treat endometriosis in women to see how they can better manage the condition.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 19 Years to 48 Years |
| Sex | Women only |
| Enrollment | 230 (estimated) |
| Sponsor | Turku University Hospital Government |
| Locations | 4 sites (Helsinki and 3 other locations) |
| Status | Recruiting |
| Started | October 2005 |
| Main results expected | December 2025 |
| Study ends | December 2028 |
| Registry record updated | August 16, 2021 |
| Trial ID | NCT01301885 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include women with surgically confirmed endometriosis and those without the condition for comparison.
✕Probably not a fit
Patients with significant other diseases, malignancy suspicion, or those who are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on endometriosis, a chronic condition affecting many women, characterized by the presence of endometrial tissue outside the uterus. It aims to explore novel diagnostic tools and treatment options, including surgical interventions like laparoscopy and laparotomy. The study will involve women with surgically and pathologically verified endometriosis as well as a control group without the condition. The goal is to better understand the disease and improve management strategies for those affected.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and treatment options for women suffering from endometriosis.
How similar studies have gone: Other studies have explored treatments for endometriosis, but the specific diagnostic tools and approaches in this study may offer novel insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * study group: surgically and pathologically verified endometriosis * control group: existence of endometriosis ruled out in laparoscopy Exclusion Criteria: * no other significant disease or medication for other diseases * suspicion of malignancy * pregnancy * acute infection * insufficient understanding of Finnish language * previous hysterectomy and/or bilateral salpingo-oophorectomy
Where it's running
-
Dept of Obstetrics and Gynecology, Turku University Central Hospital
Turku, Finland Recruiting -
Dept of Obstetrics and Gynecology, Helsinki University Hospital
Helsinki, Finland Completed -
Dept of Obstetrics and Gynecology, North Carelia Central Hospital
Joensuu, Finland Completed -
Dept of Obstetrics and Gynecology, Päijät-Häme Central Hospital
Lahti, Finland Completed
Study contacts
- Principal investigator: Antti Perheentupa, MD, PhD — Department of Obstetrics and Gynecology, Turku University Central Hospital
- Study coordinator: Antti H Perheentupa, MD PhD
- Email: antti.perheentupa@utu.fi
- Phone: +358-2-3130000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Comparing different techniques to treat endometriosis
This study is testing different methods to treat endometriosis, like laser and heat techniques, to see which one works best for relieving pain in women who are already having surgery for the condition.
-
Postoperative Pain Trajectories After Endometriosis Surgery
This study tests how pain changes after endometriosis surgery and whether perioperative pain testing can predict who will have ongoing pain.
-
Imaging endometriosis with a special PET tracer in adult women
This study tests whether a PET/CT scan using [18F]AlF-FAPI-74 can help detect endometriosis lesions in women who are planning laparoscopy.
-
Fiber supplement for digestive symptoms in endometriosis
A fiber-based supplement is being tested to see if it is safe and helps with gut and vaginal microbiomes and digestive symptoms in women with endometriosis.
-
Stellate ganglion block and dexmedetomidine for better sleep after gynecologic laparoscopy
The study tests whether giving a preoperative stellate ganglion block plus intraoperative dexmedetomidine improves sleep after laparoscopic gynecologic surgery in women.
-
Atypical Endometriosis: Histology, Immunophenotype and Molecular Features
Researchers will look at how endometriotic tissue that looks atypical under the microscope relates to clinical features and ultrasound findings to better separate benign from potentially atypical lesions.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.