Neurofeedback for improving motor recovery after stroke
Impact of Personalization of a Neurofeedback-EEG Rehabilitation Protocol on Motor Recovery in the Subacute Phase Post-stroke (CUSTOM-NF-STROKE)
This study tests if a new type of brain training called neurofeedback can help people recover movement in their arms after a stroke.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 44 (estimated) |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Sponsor | University Hospital, Toulouse Academic / other |
| Locations | 1 site (Toulouse) |
| Trial ID | NCT06212219 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of neurofeedback (NF) in enhancing motor recovery in patients who have experienced a cerebrovascular accident (CVA). It compares a standard NF procedure with a personalized NF approach tailored to individual patient needs based on feedback from questionnaires. The methodology involves providing real-time sensory feedback related to brain activity during motor tasks, aiming to improve the synchronization between attempted movements and therapist-assisted mobilization. The goal is to promote synaptic plasticity and facilitate motor recovery in the upper limb of post-stroke patients.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who have experienced a hemiplegic stroke and are in the subacute phase of recovery.
Not a fit: Patients with severe cognitive impairments or other neurological conditions affecting motor function may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve motor recovery and quality of life for stroke survivors.
How similar studies have performed: Previous meta-analyses have shown positive effects of neurofeedback in similar rehabilitation contexts, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Man, woman, over 18 years old * Motor deficit of the upper limb type of hemiplegia, secondary to a hemorrhagic or ischemic stroke authenticated by brain imaging (MRI or CT) * Post-stroke patients in the subacute phase, between 15 days and 6 months after the stroke * Correct or corrected vision allowing reading at a distance of 0 to 2m * Ability to maintain a seated position for 1 hour * Patient affiliated to a social security scheme or beneficiary of such a scheme * Informed patient having signed consent Exclusion Criteria: * Minors (age \< 18 years) * Phasic disorder limiting comprehension corresponding to a Boston Diagnostic Aphasia Examination (BDAE) score \< 4 * Attentional disorder not allowing sufficient attention to be maintained for 1 hour * History of known stroke with motor sequelae. * Known peripheral neurological pathology affecting the paretic upper limb. * Other known central neurological pathology * Factors hindering EEG acquisition (scalp pathology, abnormal cervico-cephalic movements, cranial metal implants) * Unstabilized epilepsy * Refusal to participate in the study * Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision * Pregnant, parturient, or breastfeeding patient
Where this trial is running
Toulouse
- CHU de TOULOUSE — Toulouse, France (Recruiting)
Study contacts
- Principal investigator: GASQ David, MD — University Hospital, Toulouse
- Study coordinator: GASQ David, MD
- Email: gasq.d@chu-toulouse.fr
- Phone: 5 61 32 28 42
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.