Training to improve arm and hand function after stroke

Comparing the Effect of a Graded Repetitive Arm Supplementary Home-based Exercise Programme With COgnitive-somatoSensory-MOtor Training to Improve Arm and Hand Function After Stroke (iCOSMO)

NA · University Health Network, Toronto · NCT06498011

This study is testing a special training program to see if it can help people who have had a stroke improve their arm and hand function better than a regular home exercise program.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Health Network, Toronto (other)
Locations1 site (Toronto, Ontario)
Trial IDNCT06498011 on ClinicalTrials.gov

What this trial studies

The iCOSMO study evaluates the feasibility and effectiveness of a combined sensory-motor intervention with a cognitive approach to enhance upper limb recovery in individuals who have experienced a chronic stroke. This two-arm randomized controlled trial will recruit 40 participants, dividing them into an experimental group receiving 36 hours of specialized training and a control group undergoing a home-based exercise program. The intervention includes active touch and movement tasks, along with robotic training using the Kinarm Exoskeleton device. Outcomes will be assessed through feasibility metrics and standardized clinical evaluations at various stages of the study.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old who are more than 6 months post-stroke and have motor or sensory deficits in their upper limbs.

Not a fit: Patients with upper limb deficits due to non-stroke conditions or those unable to cooperate or provide consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve arm and hand function in stroke survivors, enhancing their quality of life.

How similar studies have performed: Other studies have shown promise with similar sensory-motor training approaches, indicating potential for success in this novel intervention.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical diagnosis of stroke
* Must be more than 6 months post-stroke
* Must be above 18 years old
* Must have some motor and/or somatosensory deficits in the upper limbs

Exclusion Criteria:

* A prior history of central nervous system dysfunction other than stroke
* Upper limb deficits resulting from non-stroke pathology
* Inability to cooperate, follow instructions or provide consent

Where this trial is running

Toronto, Ontario

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stroke, CVA, Cerebrovascular Accident

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.