Nature-based virtual reality program for depression in Alzheimer's patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This intervention involves a 4-week program utilizing nature-based virtual reality (VR) sessions delivered in-home to address behavioral and psychological symptoms of dementia (BPSD), particularly depression, in individuals with Alzheimer's disease. Participants will engage in 15-minute VR sessions twice a week, with the option for caregivers to provide feedback on the intervention. The study aims to assess the feasibility and effectiveness of VR as a non-pharmacological treatment for depression in older adults with dementia, addressing barriers such as accessibility and adherence to traditional therapies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical diagnosis of mild to early-moderate stage AD (including mixed dementia with AD) using the Diagnostic and Statistical Manual of Mental Disorders, 5th Ed. Criteria
* Age of 50 years or older
* Medical stability to participate in the trial
* Patient Health Questionnaire score 5-14
* Investigator judgement on whether the participant is comfortable with technology
* Access to WiFi and a smart device for connecting on WebEx and downloading the Fitbit and Muse applications
* Have someone available to be present during all sessions

Exclusion Criteria:

* Unstable medical or psychiatric condition, including substance use based on an investigator opinion
* Visual or hearing impairments that would impair participation
* Patient Health Questionnaire score 15-27 and/or score of 1 or 2 in section E question 1 of the Cornell Scale for Depression in Dementia
* Any other reason, which will make the study participation intolerable for the participant in the opinion of the study investigator

Where it's running

• Centre for Addictions and Mental Health (CAMH)
  Toronto, Ontario, Canada Recruiting

Study contacts

• Principal investigator: HARMEHR SEKHON, PhD — CAMH and McGill/St. Mary's Research Centre
• Study coordinator: Ashnie Sukhu, BSc
• Email: ashnie.sukhu@camh.ca
• Phone: (416) 535-8501

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.