Music therapy for children with disorders of consciousness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this parallel mixed-method study, children aged 1–18 with severe brain injury and a DoC are tested over a 10-day hospital stay. On 8 days, they receive either live music therapy or recorded familiar music in random order, with consciousness measured before and after each session. The other 2 days involve video observations comparing responses to live music, recorded music, and white noise to capture subtle changes in movement and attention. The study also explores early responses to music and how parents experience music therapy during hospitalization. The setting is The Royal Children’s Hospital in Melbourne, led by Murdoch Children’s Research Institute.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of a severe ABI, as indicated by at least one of the following:

  * Glasgow Coma Scale (GCS) 3-8 at admission to RCH
  * Mass pathology evident on neuroimaging
  * Expert opinion of treating consultant
* Diagnosis of a DoC, as indicated by at least one of the following:

  * Rancho Los Amigos Scale I, II, III or IV
  * Expert opinion of treating consultant
* Legally acceptable representative capable of understanding the informed consent document and providing consent on the participant's behalf. Interpreters will be employed as necessary.

Exclusion Criteria:

* ABI not compatible with life/child expected to die
* ABI resulting from suspected non-accidental causes, including assault/abuse
* Diagnosed premorbid or acquired severe hearing loss
* Inability or unwillingness of legally acceptable representative to give written informed consent

Where it's running

• The Royal Children's Hospital Melbourne
  Parkville, Victoria, Australia Recruiting

Study contacts

• Principal investigator: Janeen M Bower, PhD — University of Melbourne
• Study coordinator: Janeen M Bower, PhD
• Email: janeen.bower@unimelb.edu.au
• Phone: +61 418 244 312

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.