Acoustic and breathing tests for dysarthria after acquired brain injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a cross-sectional observational study of about 97–101 adults with acquired brain injury that records voice and speech, measures lung function with spirometry, and performs the Frenchay Dysarthria Assessment-2 adapted to Spanish. All assessments occur at a single baseline visit under standardized conditions to limit fatigue and variability. Acoustic, respiratory, and clinical data will be analyzed together to explore associations between phonatory/respiratory function and dysarthria presence, subtype, and severity. The protocol does not include any treatment or longitudinal follow-up.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older at the time of enrollment.

Diagnosed with acquired brain injury (ABI), including:

* Stroke
* Traumatic brain injury (TBI)
* Brain tumor
* Ability to provide written informed consent (or via a legally authorized representative if necessary).
* Cognitive function preserved, defined as a Mini-Mental State Examination (MMSE) score ≥ 24.

Exclusion Criteria:

* History of chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD) or asthma.
* History of hearing impairments that could affect speech evaluation.
* Presence of additional neurological or neurodegenerative disorders other than the acquired brain injury.
* History of voice disorders or dysphonia prior to the acquired brain injury.
* Presence of persistent pharyngeal symptoms, such as mucus, secretions, or foreign body sensation, which may interfere with speech assessment.
* Participants unable to comply with the assessment protocol or complete the required sessions.
* Presence of apahasia that prevents participation in speech tasks, such as reading, repetition, or spontaneous speech priduction.

Where it's running

• University of Salamanca
  Salamanca, Salamanca, Spain Recruiting

Study contacts

• Principal investigator: Ana-María Martín Nogueras, Investigator/ Profesor — University of Salamanca
• Study coordinator: AHMED ARGOUBI, Speech Language Pathologist
• Email: ahmedargoubi@usal.es
• Phone: +34 652555591

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.