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Clinical trials and research at Murdoch Childrens Research Institute

• 25Clinical trials
• 2NIH research projects
• 9Countries

Newest trials

All recruiting trials (25)

• Speech therapy for kids with rare genetic conditions and childhood apraxia of speech

  This study tests whether 4 weeks of targeted speech therapy can improve speech accuracy in children with childhood apraxia of speech and rare genetic conditions, using one treatment approach per child.

  Recruiting Murdoch Childrens Research Institute · Melbourne, Victoria · NCT07815249

• Stop antibiotics early when symptoms stop in kids after IV treatment

  This trial tests whether stopping oral antibiotics as soon as symptoms disappear is just as effective as finishing the prescribed course for kids who had IV antibiotics for cellulitis, UTI, LRTI, or lymphadenitis.

  Recruiting Phase 4 Murdoch Childrens Research Institute · Melbourne, Victoria · NCT07532941

• Impact of Lung Pressure Levels During MIST on Preterm Babies’ Lung Aeration

  This study tests whether applying a lung recruitment maneuver before minimally invasive surfactant therapy helps preterm infants breathe more easily.

  Recruiting Murdoch Childrens Research Institute · Saint Albans, Victoria · NCT07522346

• Long-term follow-up after 18 months of oral immunotherapy for peanut, egg, or milk allergy (5–15 years later)

  This follow-up will see if children and young people who completed an 18-month oral immunotherapy for peanut, egg, or milk allergy still have changes in allergy tests and better quality of life 5–15 years later.

  Recruiting Murdoch Childrens Research Institute · Parkville, Victoria · NCT07359183

• Exercise and activity tracking during early treatment for children with ALL to prevent muscle loss and frailty

  This pilot test tries a home-based physical activity and strengthening program with a Fitbit for children aged 5–17 who show early muscle weakness after starting treatment for acute lymphoblastic leukaemia to see if it prevents muscle loss and improves strength compared with usual care.

  Recruiting Murdoch Childrens Research Institute · Melbourne, Victoria · NCT07325305

• Optimising breathing support at extubation for very preterm infants

  This trial will try starting nasal CPAP before removing the breathing tube versus starting it after extubation to see if that reduces oxygen drops in very preterm infants.

  Recruiting at 3 sites Murdoch Childrens Research Institute · Melbourne, Victoria and 2 other locations · NCT07251790

• Music therapy for children with disorders of consciousness

  This study tests whether live or recorded familiar music helps children with disorders of consciousness after severe brain injury to wake up or engage more.

  Recruiting Murdoch Childrens Research Institute · Parkville, Victoria · NCT07209657

• TAG TEAM: Group CBT for minority stress in trans and gender diverse teens

  This trial tests a group CBT program to help trans and gender diverse adolescents cope with minority stress and improve mood and wellbeing.

  Recruiting Murdoch Childrens Research Institute · Parkville, Victoria · NCT07151079

• Families' views on antibiotic length and using a smartwatch to track children's symptoms

  We will see if families are comfortable with shorter antibiotic courses and if a Garmin smartwatch can help track symptoms in children aged 4–17 with uncomplicated infections.

  Recruiting Murdoch Childrens Research Institute · Melbourne, Victoria · NCT07093749

• Speech-generating device to help communication in childhood dementia

  This project will test whether giving children with childhood dementia a speech-generating iPad app helps them communicate better than their usual care.

  Recruiting Murdoch Childrens Research Institute · Melbourne, Victoria · NCT07039084

• Wearables and machine learning to spot infections early in children and teens with cancer

  This project will try to use data from wearable devices and machine learning to detect infections earlier in children and adolescents receiving cancer treatment.

  Recruiting Murdoch Childrens Research Institute · Parkville, Victoria · NCT07030998

• Long-term effects of jack jumper ant venom immunotherapy

  This trial will test whether people who completed 3–6 years of jack jumper ant venom immunotherapy still have protection when given a supervised sting challenge after being off treatment for 18 months to 5 years.

  Recruiting at 3 sites Phase 4 Murdoch Childrens Research Institute · Adelaide, South Australia and 2 other locations · NCT06935890

• Fertility-preservation decision aid for parents and adolescent and young adult cancer survivors

  This research tests whether adding a fertility preservation decision aid to standard information helps parents and adolescent and young adult cancer survivors better meet their fertility information needs.

  Recruiting Murdoch Childrens Research Institute · Melbourne, Victoria · NCT06894810

• Using AI to screen infants for hip dysplasia

  This study is testing if using AI with ultrasounds can help doctors find hip dysplasia in infants better than regular ultrasounds.

  Recruiting Murdoch Childrens Research Institute · Parkville, Victoria · NCT06647225

• Optimizing Ganciclovir Dosing for Immunocompromised Children with CMV

  This study is testing a new way to give ganciclovir to immunocompromised children with CMV to see if personalized dosing helps them clear the virus better than standard dosing.

  Recruiting at 7 sites Phase 2 Murdoch Childrens Research Institute · Sydney, New South Wales and 6 other locations · NCT06574789

• Genotype-informed dosing of tacrolimus for children after organ transplants

  This study tests if adjusting the dose of tacrolimus based on children's genetic makeup can help them after organ transplants by ensuring they get the right amount of the medication.

  Recruiting Phase 4 Murdoch Childrens Research Institute · Melbourne, Victoria · NCT06529536

• Change in how kids and young adults with Hodgkin or non-Hodgkin lymphoma process medicines

  This study will test whether giving small probe medicines can show changes in how children and young adults (ages 6–25) with Hodgkin or non-Hodgkin lymphoma metabolize drugs during their cancer treatment.

  Recruiting Phase 1 Murdoch Childrens Research Institute · Melbourne, Victoria · NCT06383338

• Comparing Morphine and Oxycodone for Pain Relief in Children After Surgery

  This study is testing whether morphine or oxycodone works better for relieving pain in children aged 6 to 18 after surgery and how each medication affects side effects like nausea.

  Recruiting Phase 4 Murdoch Childrens Research Institute · Melbourne, Victoria · NCT06186141

• Evaluating medical oxygen access and policies

  This study looks at how access to medical oxygen works in six countries to see what challenges people face and how to improve it for patients and healthcare providers.

  Recruiting at 6 sites Murdoch Childrens Research Institute · Phnom Penh and 5 other locations · NCT06169514

• Evaluation of a multi-country medical oxygen program

  This study is trying to see how medical oxygen is used in hospitals across nine countries to find ways to make it easier for patients, especially children with low oxygen levels, to get the help they need.

  Recruiting Murdoch Childrens Research Institute · Phnom Penh and 2 other locations · NCT06087315

• Targeted therapies for patients with vascular malformations

  This study is testing new targeted treatments for patients with slow-flow and fast-flow vascular malformations to see if they work better than the usual therapies.

  Recruiting at 2 sites Phase 2 Murdoch Childrens Research Institute · Parkville, Victoria and 1 other locations · NCT05983159

• Improving vancomycin dosing for young infants with infections

  This study is testing a new way to give the right amount of vancomycin to young infants with infections to help them get better faster.

  Recruiting at 2 sites Phase 4 Murdoch Childrens Research Institute · Melbourne, Victoria and 3 other locations · NCT05770622

• Longitudinal study of Victorian children and their parents

  This study is looking at the health and wellbeing of children born in Victoria and their parents over time to see how different factors affect their physical and mental health.

  Recruiting Murdoch Childrens Research Institute · Parkville, Victoria · NCT05394363

• One dose of intravenous antibiotics for complicated urinary tract infections in children

  This study is testing if giving children with complicated urinary tract infections one dose of intravenous antibiotics followed by two days of oral antibiotics works just as well as the usual three doses of intravenous antibiotics.

  Recruiting at 7 sites Phase 4 Murdoch Childrens Research Institute · Adelaide, South Australia and 6 other locations · NCT04876131

• Oral antibiotics for treating bone and joint infections in children

  This study tests if giving only oral antibiotics can effectively treat bone and joint infections in children, compared to the usual method that starts with IV antibiotics.

  Recruiting at 9 sites Phase 4 Murdoch Childrens Research Institute · Kingswood, New South Wales and 10 other locations · NCT04538053

NIH-funded research (2)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Developing vaccines to prevent infections from Group A Streptococcus

  This study is working on developing better vaccines to protect people from Group A Streptococcus infections by using human samples and a new tissue model to understand how our immune system fights this bacteria.

  NIH research Murdoch Children's Research Institute · Melbourne, Australia · NIH-10992610

• Investigating how gender-affirming hormone therapy affects immune function

  This study is looking at how hormone therapy affects the immune system in transgender people, specifically by checking blood samples from transgender women before and after they start treatment to see how the hormones might change their immune responses and risk of infections.

  NIH research Murdoch Children's Research Institute · Melbourne, Australia · NIH-10912044

Quick answers

How many clinical trials run by Murdoch Childrens Research Institute are recruiting right now?

25, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in Australia (23 trials), New Zealand (3 trials), Cambodia (2 trials), Nigeria (2 trials), Uganda (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 7, Phase 2: 2, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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