Multilayered PRF versus connective tissue graft for anterior implant tissue health

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares multilayered PRF membranes with the standard connective tissue graft during the second-stage surgery around single anterior dental implants. It focuses on enhancing peri-implant mucosal thickness and the width of keratinized tissue to achieve better esthetics. Outcomes center on tissue stability and healing in the anterior esthetic zone, with a 2nd-stage healing period. Eligible participants are adults 21–65 with good oral hygiene and a single missing tooth in the esthetic area. Smokers and medically compromised individuals are excluded to limit healing confounders.

Why it matters

Who can join: the full rules

-Inclusion Criteria: Patients with single bounded missing tooth in the esthetic zone Patients in the age group of 21-65 years Patients having good oral hygiene (mean plaque score of \< 25%) and with stable periodontal status.

-Exclusion Criteria: Smokers patients Patients with poor maintenance of oral hygiene, as determined by a mean plaque score of ≥ 25% despite efforts by the clinician to improve oral hygiene maintenance.

Patients with medically compromised conditions like uncontrolled diabetes mellitus or any systemic diseases that may result in compromised hard and soft tissue healing.

Where it's running

• Gulf Medical University
  Ajman, Ajman Emirate, United Arab Emirates Recruiting

Study contacts

• Study coordinator: Nesma Shemais, PhD
• Email: dr.nesma@gmu.ac.ae
• Phone: 0529961988

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Grafting Techniques for Thin Gingival Tissues with Delayed Implants

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• How Smoking Affects Immune Responses Around Dental Implants

  This study tests how smoking changes the body's immune response around dental implants in people with healthy implants, peri-implant mucositis, or peri-implantitis.

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• Buccal fat pad versus palatal pedicle flap for soft tissue coverage over zygomatic implants in a severely atrophied upper jaw

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• Buccal fat pad versus platelet-rich fibrin to cover zygomatic implants

  We will test whether using the buccal fat pad or platelet-rich fibrin to cover zygomatic implants leads to thicker gum tissue and fewer complications for people with severely atrophic upper jaws receiving zygomatic implants.

  Recruiting Cairo University · Cairo, Cairo Governorate · NCT07562334

• Gum tissue build-up at a missing-tooth pontic site with or without a fixed partial denture

  We will test whether connective tissue grafts can improve gum thickness and contour at a single missing-tooth site in adults, comparing sites that have an existing fixed partial denture to sites without one.

  Recruiting Cairo University · Cairo · NCT07535060

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.