Buccal fat pad versus platelet-rich fibrin to cover zygomatic implants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized clinical trial will compare two soft-tissue coverage techniques—buccal fat pad (BFP) and platelet-rich fibrin (PRF)—used to cover the body of zygomatic implants placed for reconstruction of a severely atrophic posterior maxilla. Eligible patients with Cawood class IV–VI edentulous upper arches and sufficient anterior bone for two conventional implants will be randomized to receive either BFP or PRF coverage at a single center. Primary outcomes include peri-implant soft tissue thickness, rates of mucosal dehiscence, and other postoperative complications measured through the immediate loading phase and up to final restoration. The trial aims to identify which coverage method provides a more stable soft tissue profile with fewer complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with severely atrophic edentulous upper arch (Cawood class IV, V, VI) that could not be restored by other type of treatment
2. Patients who had at least 8-12 mm vertical bone height in anterior maxilla to allow installation of 2 conventional implants.
3. Lacking posterior maxillary bone support due to significant sinus pneumatization
4. Good systemic health (ASA score I-II)
5. Highly motivated patients

Exclusion Criteria:

1. Patient not willing to give his/her informed consent.
2. Patients with systemic disease that did not permit the surgical procedure (including general anesthesia).
3. Patients with uncontrolled diabetes or under bisphosphonate therapy.
4. Heavy smoker. (\> 20 cigarettes daily)
5. Patient with psychiatric problems, severe bruxism or other parafunctional habits.
6. Acute sinusitis.
7. Malignancy or pathology in Maxilla or Zygoma.

Where it's running

• Cairo university, Faculty of dentistry
  Cairo, Cairo Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Caroline John Caroline John George, masters
• Email: caroline.john@dentistry.cu.edu.eg
• Phone: +201282101184

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• How different implant abutment shapes and heights affect bone loss around dental implants

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.