Grafting Techniques for Thin Gingival Tissues with Delayed Implants
Official title: The Effect of De-epithelized Connective Tissue Graft Versus Sub-epithelized Connective Tissue Graft in Management of Thing Gingival Phenotype With Delayed Implants
Run by Future University in Egypt · NCT07892820 · Data updated 2026-11-12
This study tests whether sub-epithelized versus de-epithelized connective tissue grafts improve outcomes for delayed dental implants in people with thin gums.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 50 Years |
| Sex | All |
| Enrollment | 24 (estimated) |
| Sponsor | Future University in Egypt Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | January 30, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | January 30, 2027 |
| Registry record updated | October 29, 2026 |
| Trial ID | NCT07892820 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults 20–50 with thin gingival phenotype (<1.5 mm), a single edentulous area, no periodontal disease, non-smokers, and suitable palatal graft thickness (≥2 mm) and bone width (≥8 mm).
✕Probably not a fit
Patients with periodontal disease, systemic conditions, smoking, or unsuitable graft/bone dimensions may not benefit from the graft strategies tested.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares two connective tissue graft methods used with delayed dental implant placement in patients with a thin gingival phenotype. Participants will be adults aged 20–50 with single edentulous areas and specific gum and bone criteria, and who are non-smokers with no periodontal disease. Outcomes will focus on the stability and aesthetics of peri-implant soft tissues after grafting, comparing sub-epithelized and de-epithelized graft approaches. The study is conducted at Future University in Egypt and aims to inform best practices for soft-tissue management in implant dentistry.
Why it matters
Potential benefit: If successful, the graft method that better maintains peri-implant soft tissue could improve implant longevity and cosmetic results.
How similar studies have gone: Previous studies have explored connective tissue grafts in implant dentistry, indicating potential benefits, but direct comparison of sub-epithelized versus de-epithelized grafts in delayed implants is less established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Thin gingival phenotype \< 1.5mm.\[6\] * Medical free. * Single edentulous area. * Age range is between 20 to 50 years. * Gingival recession. * Free from any periodontal disease. * Positive patient's acceptance for participating in the study. * Patients able to sign informed consent. * Non-smokers. * Moderate palatal vault. * Thickness of palatal graft not \<2mm. * Width of bone not \<8mm. Exclusion Criteria: * Psychologically disturbed patients. * Patients with a history of allergy to any medication used in the study were excluded. * Osteoporosis. * Parafunctional habit. * Patients taking anticoa * Gulant therapy.
Where it's running
-
Future University in Egypt
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Hossam Rushdy Master Candidate, Bachelor Degree
- Email: Hosam.Roshdy.1996@hotmail.com
- Phone: +20 11 55436000
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Multilayered PRF versus connective tissue graft for anterior implant tissue health
This study tests whether multilayered platelet-rich fibrin can improve soft tissue around front-mouth dental implants as well as the traditional connective tissue graft.
-
Gum tissue build-up at a missing-tooth pontic site with or without a fixed partial denture
We will test whether connective tissue grafts can improve gum thickness and contour at a single missing-tooth site in adults, comparing sites that have an existing fixed partial denture to sites without one.
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Fully digital workflow for immediate implants with same-day restoration
This project tests whether a fully digital workflow can give adults who need a single immediate implant with a same-day temporary crown the same implant survival, bone stability, and patient satisfaction as the standard analog approach.
-
Comparing two surgical methods for improving soft tissue volume in dental procedures
This study is testing which of two surgical methods, a connective tissue graft or a collagen matrix, works better to improve soft tissue volume around dental implants for patients.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.