Clinical trial Recruiting at 1 site Interventional Ages 20 to 50

Grafting Techniques for Thin Gingival Tissues with Delayed Implants

Official title: The Effect of De-epithelized Connective Tissue Graft Versus Sub-epithelized Connective Tissue Graft in Management of Thing Gingival Phenotype With Delayed Implants

Run by Future University in Egypt · NCT07892820 · Data updated 2026-11-12

This study tests whether sub-epithelized versus de-epithelized connective tissue grafts improve outcomes for delayed dental implants in people with thin gums.

Quick facts

Study typeInterventional
Ages20 Years to 50 Years
SexAll
Enrollment24 (estimated)
SponsorFuture University in Egypt
Academic / other
Locations1 site (Cairo)
StatusRecruiting
StartedJanuary 30, 2025
Main results expectedDecember 31, 2026
Study endsJanuary 30, 2027
Registry record updatedOctober 29, 2026
Trial IDNCT07892820 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults 20–50 with thin gingival phenotype (<1.5 mm), a single edentulous area, no periodontal disease, non-smokers, and suitable palatal graft thickness (≥2 mm) and bone width (≥8 mm).

Probably not a fit

Patients with periodontal disease, systemic conditions, smoking, or unsuitable graft/bone dimensions may not benefit from the graft strategies tested.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two connective tissue graft methods used with delayed dental implant placement in patients with a thin gingival phenotype. Participants will be adults aged 20–50 with single edentulous areas and specific gum and bone criteria, and who are non-smokers with no periodontal disease. Outcomes will focus on the stability and aesthetics of peri-implant soft tissues after grafting, comparing sub-epithelized and de-epithelized graft approaches. The study is conducted at Future University in Egypt and aims to inform best practices for soft-tissue management in implant dentistry.

Why it matters

Potential benefit: If successful, the graft method that better maintains peri-implant soft tissue could improve implant longevity and cosmetic results.

How similar studies have gone: Previous studies have explored connective tissue grafts in implant dentistry, indicating potential benefits, but direct comparison of sub-epithelized versus de-epithelized grafts in delayed implants is less established.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Thin gingival phenotype \< 1.5mm.\[6\]
* Medical free.
* Single edentulous area.
* Age range is between 20 to 50 years.
* Gingival recession.
* Free from any periodontal disease.
* Positive patient's acceptance for participating in the study.
* Patients able to sign informed consent.
* Non-smokers.
* Moderate palatal vault.
* Thickness of palatal graft not \<2mm.
* Width of bone not \<8mm.

Exclusion Criteria:

* Psychologically disturbed patients.
* Patients with a history of allergy to any medication used in the study were excluded.
* Osteoporosis.
* Parafunctional habit.
* Patients taking anticoa
* Gulant therapy.

Where it's running

  • Future University in Egypt
    Cairo, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.