MTP block vs ESP block for pain control after VATS
Official title: A Randomized, Double-Blind Controlled Trial Comparing the Effectiveness of Midpoint Transverse Process to Pleura (MTP) Block and Erector Spinae Plane (ESP) Block in Video-Assisted Thoracoscopic Surgery (VATS) at RS Ngoerah
Run by Udayana University · NCT07868484 · Data updated 2026-11-12
This trial tests whether the MTP block provides better pain relief than the ESP block after video-assisted thoracoscopic surgery in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 51 (estimated) |
| Sponsor | Udayana University Academic / other |
| Locations | 1 site (Denpasar, Bali) |
| Status | Recruiting |
| Started | June 4, 2026 |
| Main results expected | September 3, 2026 |
| Study ends | October 4, 2026 |
| Registry record updated | October 9, 2026 |
| Trial ID | NCT07868484 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–65 undergoing elective VATS, ASA I–III, BMI 18–30, able to consent and complete pain and QoR-15 assessments.
✕Probably not a fit
Patients with contraindications to regional anesthesia or inability to use the pain scales or PCA may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, double-blind study compares two ultrasound-guided fascial plane blocks—midpoint transverse process to pleura (MTP) block and erector spinae plane (ESP) block—for postoperative analgesia in adults undergoing elective VATS. Each participant receives a single injection of ropivacaine 0.375% at the T4–T5 level after induction of general anesthesia. The primary outcome is total fentanyl consumption via patient-controlled analgesia in the first 24 hours postoperatively, with secondary outcomes including pain scores at multiple time points and time to first analgesia. All patients receive standardized general anesthesia, multimodal analgesia, and identical postoperative fentanyl PCA. The study is conducted at RS Ngoerah in Denpasar, Indonesia, sponsored by Udayana University.
Why it matters
Potential benefit: If successful, the preferred block could reduce opioid needs and improve early postoperative comfort after VATS.
How similar studies have gone: While both blocks are used for thoracic analgesia, direct randomized comparisons in VATS are limited, making this study relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients scheduled for elective video-assisted thoracoscopic surgery (VATS) at RS Ngoerah * Age 18-65 years * ASA physical status I-III * Body mass index 18-30 kg/m2 * Able to communicate well in Indonesian, understand the use of the Numerical Rating Scale, and complete the QoR-15 questionnaire * Willing to participate and has signed written informed consent Exclusion Criteria: * Contraindication to regional anesthesia * Allergy to the drugs used (ropivacaine, fentanyl, paracetamol and/or ibuprofen) * Chronic chest pain for more than 2 months before surgery * Unable to be assessed with the Numerical Rating Scale and unable to operate the PCA device
Where it's running
-
RS Ngoerah
Denpasar, Bali, Indonesia Recruiting
Study contacts
- Study coordinator: Lalu Reza Aldira Akbar, MD
- Email: aldeeraakbar@gmail.com
- Phone: +6281337871680
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.