Mouth opening and cheek muscle stiffness after oral cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study uses strain elastography ultrasound to measure the elasticity of the masseter muscle in patients who have undergone oral cancer treatment. It examines the relationship between muscle hardness (masseter elasticity index) and maximum mouth opening. The study also tests a structured exercise program to see if changes in muscle stiffness can predict improvements in trismus. Participants will be scanned to measure MEI and MIO before and after the intervention, with analysis exploring potential associations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Newly diagnosed oral cancer patients who are scheduled to receive cancer-related treatments (e.g., oral cancer surgery, radiotherapy, chemotherapy, or chemoradiotherapy).
2. Age between 20 and 65 years.

Exclusion Criteria:

1. Could not communicate.
2. Had any disorder that could influence movement performance.

Where it's running

• National Taiwan University
  Taipei, Taiwan Recruiting

Study contacts

• Principal investigator: Yueh-Hsia Chen, PhD — National Taiwan University, College of Medicine
• Study coordinator: Yueh-Hsia Chen, PhD
• Email: yuehhsiachen@ntu.edu.tw
• Phone: +886-2-33668133

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.