Hydrogen water oral care after free flap reconstruction for oral cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind, parallel-group trial compares hydrogen water oral care to boiled water oral care in adults who had microsurgical free flap reconstruction for oral cancer. Participants receive 7 days of guided oral care with the assigned beverage, with saliva samples and pain assessments taken at baseline, day 3, and day 7. Outcomes focus on acute oral inflammation, microbiota changes, and patient-reported pain, using standardized assessments. The study uses computer-generated randomization and blinding of participants and care providers to group assignment. Safety and consent procedures are described, with monitoring during hospitalization.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with oral cancer and undergoing microsurgical flap reconstruction.
* Age 18 years or older.
* Clear consciousness.
* Able to communicate without difficulty in Mandarin, Taiwanese, or in writing.

Exclusion Criteria:

* Abnormal salivary secretion function or severe xerostomia.
* Use of antibacterial mouthwash after surgery.

Where it's running

• Kaohsiung Medical University Chung-Ho Memorial Hospital
  Kaohsiung City, Taiwan Recruiting

Study contacts

• Principal investigator: I-Shan Chou, Ms — Kaohsiung Medical University Chung-Ho Memorial Hospital
• Study coordinator: I-Shan Chou, Ms
• Email: awoponn20@gmail.com
• Phone: +886-917-520-113

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.