Monitoring and understanding chronic pain using AI and telemonitoring

Unveiling Physiological and Psychosocial Pain Components with an Artificial Intelligence Based Telemonitoring Tool (pAIn-sense)

Observational ETH Zurich · NCT06044584

This study is testing a new way to manage chronic pain by using wearable technology and AI to better understand patients' pain experiences and improve their treatment.

Quick facts

Study typeObservational
Enrollment150 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorETH Zurich Academic / other
Locations4 sites (Pietra Ligure, Savona and 3 other locations)
Trial IDNCT06044584 on ClinicalTrials.gov

What this trial studies

The pAIn-sense study aims to transform chronic pain management by utilizing an advanced telemonitoring system that combines Artificial Intelligence and wearable technology. This observational study will continuously gather multidimensional data on patients' physiological and psychosocial conditions, providing a comprehensive understanding of their pain experiences. By addressing the limitations of traditional pain management approaches, the study seeks to identify biomarkers and reliable endpoints for pain assessment, ultimately leading to more personalized treatment strategies. The focus is on both nociceptive and neuropathic pain, with the goal of improving patient outcomes and satisfaction.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals experiencing ongoing nociceptive or neuropathic pain who are comfortable using electronic devices.

Not a fit: Patients who may not benefit include those unable to follow study procedures due to language barriers, psychological disorders, or cognitive impairments.

Why it matters

Potential benefit: If successful, this study could lead to more effective and personalized pain management strategies for patients suffering from chronic pain.

How similar studies have performed: While the approach of using AI and telemonitoring for pain management is innovative, similar studies have shown promise in enhancing pain assessment and treatment personalization.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ongoing nociceptive pain after an injury or Neuropathic pain (acute or chronic)
* Familiar with using electronic devices

Exclusion Criteria:

* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc.
* Unable or not willing to give informed consent

Where this trial is running

Pietra Ligure, Savona and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Nociceptive PainNeuropathic PainPainTelemonitoringArtificial IntelligencePhysiological signalsPsychosocial
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.