PBMT with a pulmonary rehab program for COPD patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind, placebo-controlled trial investigates whether photobiomodulation therapy (PBMT) added to a standard pulmonary rehabilitation program improves functional capacity in COPD patients. Twenty participants with moderate-to-severe COPD are assigned to active PBMT or placebo, receiving treatments before the rehab exercises over eight weeks (16 sessions total). The study keeps the rehab protocol identical for all participants and uses sham PBMT in the control group. Primary outcomes focus on functional capacity, with eligibility limited to adults with COPD in the maintenance phase who can walk. The trial is conducted at Santa Casa de Porto Alegre with sponsorship from the Federal University of Health Science of Porto Alegre.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients diagnosed with COPD, in the maintenance phase, with GOLD classification 3 and 4;
* Ability to walk.

Exclusion Criteria:

* Cognitive dysfunction that prevents the completion of assessments, as well as inability to understand and sign the informed consent form (ICF);
* Patients with sequelae of stroke;
* Recent acute myocardial infarction (within two months);
* Uncontrolled hypertension;
* Heart failure grade IV according to the New York Heart Association or decompensated;
* Unstable angina or arrhythmia;
* Peripheral vascular alterations in lower limbs such as deep vein thrombosis;
* Disabling osteoarticular or musculoskeletal disease;
* Patients with cancer and/or undergoing cancer treatment;
* Patients with systemic lupus erythematosus;
* Pacemaker or cardiac defibrillator;
* Hemophilia;
* Recent skin lesions or tattoos at the site of therapy application.

Where it's running

• Santa Casa de Porto Alegre
  Porto Alegre, Rio Grande do Sul, Brazil Recruiting

Study contacts

• Study coordinator: Jociane J Schardong, PHD
• Email: jocianeschardong@gmail.com
• Phone: +55 (51) 981348114

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.