Metabolic phenotypes linked to obesity risk in young infants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational research measures infants' energy expenditure and respiratory exchange ratio before and after two standardized meal tests (human milk and infant formula). Changes in energy use and substrate oxidation will be calculated from pre- and post-meal measurements, and a DXA scan will assess body composition. Investigators will use those post-meal responses to classify infants as having metabolic 'thriftiness' (lower postprandial energy expenditure) or metabolic 'flexibility' (larger shifts in substrate oxidation). The protocol enrolls infants aged 2 to less than 17 weeks who are primarily breastfed and willing to take one formula meal, with visits at the Pennington Biomedical Research Center in Baton Rouge.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 2 weeks to less than 17 weeks at screening
* Being fed human milk as a primary source of food
* Be willing to consume one meal of infant formula
* Be willing to complete a DXA measurement

Exclusion Criteria:

* Unable to complete the screening visit and two clinic visits within 14 days
* Born with health conditions that would render procedures unsafe
* Born earlier than 35 days and 0 weeks gestation
* Eating supplemental foods
* Physician diagnosed feeding difficulties that may require a special type of nipple for bottle feeding

Where it's running

• Pennington Biomedical Research Center
  Baton Rouge, Louisiana, United States Recruiting

Study contacts

• Study coordinator: Abby A Altazan, MS
• Email: abby.altazan@pbrc.edu
• Phone: 225-763-2801

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.